Expression of cellular effector functions and production of reactive nitrogen intermediates: A comparative study including T lymphocytes, T-like cells, neutrophil granulocytes, and mononuclear phagocytes

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Biosynthesis of nitric oxide from l-arginine

1989 • 1,220 citations

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

1986 • 316 citations

L-arginine-dependent reactive nitrogen intermediates as mediators of tumor cell killing by activated macrophages.

1990 • 155 citations

Second messenger role for NO widens to nervous and immunesystem

1989 • 135 citations

Mechanisms of immune lysis. II. CTL-induced nuclear disintegration of the target begins within minutes of cell contact.

1980 • 119 citations

Preferential usage of V_α4 and V_β10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein‐specific H‐2D^b‐restricted cytotoxic T cells

1990 • 89 citations

CD4+ T cell-mediated killing of MHC class II-positive antigen-presenting cells. I. Characterization of target cell recognition by in vivo or in vitro activated CD4+ killer T cells.

1990 • 86 citations

Evidence for multiple lytic pathways used by cytotoxic T lymphocytes.

1989 • 74 citations

The protein kinase c inhibitor H-7 activates human neutrophils: effect on shape, actin polymerization, fluid pinocytosis and locomotion

1990 • 43 citations

Abilities of activated macrophages to manifest tumoricidal activity and to generate reactive nitrogen intermediates: A comparative study in vitro and ex vivo

1989 • 43 citations

Morphologic analysis of human lymphokine‐activated killer (LAK) cells

1990 • 15 citations