Effects of MK-801 and antidepressant drugs in the forced swimming test in rats

Behavioral despair in mice: a primary screening test for antidepressants.

1977 • 3,241 citations

Behavioural despair in rats: A new model sensitive to antidepressant treatments

1978 • 3,035 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Is the forced swimming test a suitable model for revealing antidepressant activity?

1988 • 1,053 citations

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

1990 • 754 citations

Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity

1979 • 576 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

THE EFFECTS OF A SERIES OF ω‐PHOSPHONIC α‐CARBOXYLIC AMINO ACIDS ON ELECTRICALLY EVOKED AND EXCITANT AMINO ACID‐INDUCED RESPONSES IN ISOLATED SPINAL CORD PREPARATIONS

1982 • 463 citations

[³H]MK‐801 Labels a Site on the N‐Methyl‐D‐Aspartate Receptor Channel Complex in Rat Brain Membranes

1988 • 453 citations

Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 229 citations

A simple model for studying benzodiazepines: Potentiation of hyperactivity induced by cocaine in mice

1982 • 193 citations

MK-801-induced stereotypy and its antagonism by neuroleptic drugs

1990 • 138 citations

MK-801 potentiates dopaminergic D1 but reduces D2 responses in the 6-hydroxydopamine model of Parkinson's disease

1990 • 99 citations

Locomotor hyperactivity induced by MK-801 in rats.

1991 • 40 citations

Antidepressant drugs increase the locomotor hyperactivity induced by MK-801 in rats

1991 • 28 citations

Fluvoxamine, a new antidepressant drug, fails to show antiserotonin activity

1982 • 27 citations

Effect of Zimeldine, a New Antidepressant, on the Forced Swimming Test in Rats

1984 • 18 citations