Therapy Insight: cancer anorexia–cachexia syndrome—when all you can eat is yourself

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2000 • 629 citations

The symptoms of advanced cancer: relationship to age, gender, and performance status in 1,000 patients

2000 • 612 citations

Effect of a protein and energy dense n-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial

2003 • 590 citations

Cancer Anorexia-Cachexia Syndrome: Current Issues in Research and Management

2002 • 579 citations

Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial

2003 • 579 citations

Gene Expression Profiles Predict Complete Pathologic Response to Neoadjuvant Paclitaxel and Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy in Breast Cancer

2004 • 545 citations

Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.

2003 • 516 citations

Activation of Central Melanocortin Pathways by Fenfluramine

2002 • 481 citations

Nutrition intervention is beneficial in oncology outpatients receiving radiotherapy to the gastrointestinal or head and neck area

2004 • 474 citations

Ghrelin Increases Energy Intake in Cancer Patients with Impaired Appetite: Acute, Randomized, Placebo-Controlled Trial

2004 • 457 citations

Characterization of a cancer cachectic factor

1996 • 442 citations

Reduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with n-3 fatty acids

2004 • 423 citations

Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ

2004 • 416 citations

Cancer anorexia-cachexia syndrome: are neuropeptides the key?

1999 • 345 citations

Cancer: disease and nutrition are key determinants of patients? quality of life

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Role of the calpain system in muscle growth

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An Eicosapentaenoic Acid Supplement Versus Megestrol Acetate Versus Both for Patients With Cancer-Associated Wasting: A North Central Cancer Treatment Group and National Cancer Institute of Canada Collaborative Effort

2004 • 292 citations

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2003 • 283 citations

Effect of Fish Oil on Appetite and Other Symptoms in Patients With Advanced Cancer and Anorexia/Cachexia: A Double-Blind, Placebo-Controlled Study

2002 • 276 citations

Cancer anorexia: clinical implications, pathogenesis, and therapeutic strategies

2003 • 239 citations

Palliative nutritional intervention in addition to cyclooxygenase and erythropoietin treatment for patients with malignant disease: Effects on survival, metabolism, and function

2004 • 231 citations

Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans

2003 • 193 citations

Cancer anorexia-cachexia syndrome: cytokines and neuropeptides

2004 • 190 citations

Palliative Effect of Chemotherapy: Objective Tumor Response Is Associated With Symptom Improvement in Patients With Metastatic Breast Cancer

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Skeletal muscle metabolism in patients with malignant tumor

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Systematic review of megestrol acetate in the treatment of anorexia-cachexia syndrome

2004 • 181 citations

Increased gene expression of brown fat uncoupling protein (UCP)1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia.

2000 • 150 citations

Oral supplementation of branched‐chain amino acid improves nutritional status in elderly patients on chronic haemodialysis

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Increased muscle ubiquitin mRNA levels in gastric cancer patients

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Nutritional issues in cancer management

1996 • 134 citations

Differential Role of Melanocortin Receptor Subtypes in Cachexia

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2004 • 111 citations

Whole Body Protein Synthesis and Turnover in Normal Man and Malnourished Patients with and without Known Cancer

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What We Have Learned about Cachexia in Gastrointestinal Cancer

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Effects of Administration of Oral Branched-Chain Amino Acids on Anorexia and Caloric Intake in Cancer Patients

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Effect of cyclooxygenase and nitric oxide synthase inhibitors on tumor growth in mouse tumor models with and without cancer cachexia related to prostanoids.

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Role of Omega-3 Fatty Acid Supplementation in Inflammation and Malignancy

2004 • 79 citations

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2004 • 74 citations

Cardiovascular and metabolic response to adrenaline infusion in weight‐losing patients with and without cancer

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Effect of eicosapentaenoic acid, protein and amino acids on protein synthesis and degradation in skeletal muscle of cachectic mice

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Plasma tryptophan and anorexia in human cancer

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Management of terminal cancer in elderly patients

2003 • 48 citations

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Therapy of muscle wasting in cancer: what is the future?

2004 • 42 citations

Artificial Nutrition in Cancer Patients: Which Route, What Composition?

1999 • 32 citations

Multiple Myeloma in Mexico: A 20-year experience at a single institution

2004 • 31 citations

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2004 • 9 citations

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