Differential expression of thrombospondin 1, 2, and 3 during murine development

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

1990 • 677 citations

Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin

1991 • 560 citations

Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage.

1992 • 521 citations

Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.

1985 • 503 citations

Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors.

1988 • 481 citations

Isolation and characterization of a high molecular weight glycoprotein from human blood platelets.

1978 • 428 citations

Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.

1990 • 407 citations

The Ultrastructure and Biochemistry of Meniscal Cartilage

1990 • 394 citations

The gene family encoding the mouse ribosomal protein L32 contains a uniquely expressed intron-containing gene and an unmutated processed gene

1984 • 381 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

Thrombospondins: structure and regulation of expression

1992 • 345 citations

Synthesis and secretion of thrombospondin by cultured human endothelial cells.

1982 • 311 citations

In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization.

1987 • 292 citations

Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro.

1991 • 273 citations

Developmental expression of transforming growth factors alpha and beta in mouse fetus.

1988 • 272 citations

Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor beta. Immunohistochemical localization and association with differentiating cells.

1986 • 271 citations

Thrombospondin modulates focal adhesions in endothelial cells.

1989 • 271 citations

Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix.

1983 • 266 citations

Light microscopic immunolocation of thrombospondin in human tissues.

1985 • 265 citations

Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin.

1986 • 259 citations

Thrombospondin: synthesis and secretion by cells in culture.

1982 • 259 citations

Transforming growth factor-beta complexes with thrombospondin.

1992 • 256 citations

The properdin-like type I repeats of human thrombospondin contain a cell attachment site.

1991 • 238 citations

Vitronectin and thrombospondin promote retinal neurite outgrowth: Developmental regulation and role of integrins

1991 • 237 citations

The development of the lung in mammals: An analysis of concepts and findings

1981 • 232 citations

Isolation and characterization of a glycoprotein secreted by aortic endothelial cells in culture. Apparent identity with platelet thrombospondin.

1981 • 216 citations

Unique distribution of the extracellular matrix component thrombospondin in the developing mouse embryo.

1988 • 212 citations

Monocytes and macrophages synthesize and secrete thrombospondin

1985 • 208 citations

Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains.

1987 • 206 citations

Thrombospondin: a modular adhesive glycoprotein of platelets and nucleated cells.

1987 • 205 citations

Platelet thrombospondin mediates attachment and spreading of human melanoma cells.

1987 • 196 citations

Physiology of Thrombospondin

1990 • 195 citations

DNA Sequencing Markets

1990 • 173 citations

Thrombospondins

1991 • 169 citations

Specific inhibition of endothelial cell proliferation by thrombospondin

1990 • 168 citations

Heparin- and sulfatide-binding peptides from the type I repeats of human thrombospondin promote melanoma cell adhesion.

1992 • 163 citations

Induction of an epithelial-mesenchymal transition by an in vivo adheron-like complex

1989 • 144 citations

Transforming Growth Factor- β1, β2 and - β3 in cartilage and bone cells during endochondral ossification in the chick

1992 • 139 citations

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome

1991 • 120 citations

Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.

1992 • 118 citations

Deposition and role of thrombospondin in the histogenesis of the cerebellar cortex.

1990 • 118 citations

Thrombospondin 3 (Thbs3), a new member of the thrombospondin gene family.

1992 • 115 citations

Thrombospondin and a 140 kd fragment promote adhesion and neurite outgrowth from embryonic central and peripheral neurons and from PC12 cells

1991 • 114 citations

Immunohistochemical localization of membrane and alpha-granule proteins in human megakaryocytes: application to plastic-embedded bone marrow biopsy specimens

1986 • 114 citations

Methods in Experimental Embryology of the Mouse

1971 • 112 citations

Human brain glial cells synthesize thrombospondin.

1986 • 110 citations

CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction.

1992 • 100 citations

Thrombospondin promotes process outgrowth in neurons from the peripheral and central nervous systems

1992 • 98 citations

Methods in experimental embryology of the mouse

1970 • 95 citations

A serum response element and a binding site for NF-Y mediate the serum response of the human thrombospondin 1 gene.

1993 • 85 citations

Chinese hamster ovary cell adhesion to human platelet thrombospondin is dependent on cell surface heparan sulfate proteoglycan.

1989 • 80 citations

Colocalization of thrombospondin and syndecan during murine development

1992 • 77 citations

Role of the extracellular matrix protein thrombospondin in the early development of the mouse embryo.

1990 • 71 citations

A second thrombospondin gene in the mouse is similar in organization to thrombospondin 1 but does not respond to serum.

1991 • 66 citations

A highly conserved intronic sequence is involved in transcriptional regulation of the alpha 1(I) collagen gene.

1990 • 64 citations

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

1992 • 63 citations

Partial amino acid sequence of human thrombospondin as determined by analysis of cDNA clones: homology to malarial circumsporozoite proteins

1986 • 56 citations

Characterization of the mouse thrombospondin gene and evaluation of the role of the first intron in human gene expression.

1990 • 55 citations

Human Keratinocytes Synthesize and Secrete the Extracellular Matrix Protein, Thrombospondin

1987 • 50 citations

Thrombospondin II: Partial cDNA sequence, chromosome location, and expression of a second member of the thrombospondin gene family in humans

1992 • 49 citations

Cloning and sequencing of chicken thrombospondin

1991 • 47 citations

Thrombospondin gene expression by endothelial cells in culture is modulated by cell proliferation, cell shape and the substratum

1990 • 44 citations

Thrombospondin in ligament, meniscus and intervertebral disc

1991 • 37 citations

Cell attachment activity of the carboxyl-terminal domain of human thrombospondin expressed in Escherichia coli.

1991 • 36 citations

Human carcinoma cells bind thrombospondin through a Mr 80,000/105,000 receptor.

1991 • 35 citations

Isolation and Characterization of the Mouse Thrombospondin 3 (Thbs3) Gene

1993 • 34 citations

Thrombospondin: phenomenology to function.

1989 • 33 citations

Modulation of thrombospondin gene expression during osteoblast differentiation in MC3T3-E1 cells

1992 • 28 citations