Measurement of 3-Nitrotyrosine and 5-Nitro-γ-Tocopherol by high-performance liquid chromatography with electrochemical detection

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

1998 • 1,494 citations

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1992 • 1,319 citations

Peroxynitrite formation from macrophage-derived nitric oxide

1992 • 1,118 citations

Blood Flow Regulation by S -Nitrosohemoglobin in the Physiological Oxygen Gradient

1997 • 1,050 citations

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.

1993 • 845 citations

Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide

1998 • 800 citations

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

1992 • 758 citations

Extracellular Signal-Regulated Kinase and p38 Subgroups of Mitogen-Activated Protein Kinases Regulate Inducible Nitric Oxide Synthase and Tumor Necrosis Factor-α Gene Expression in Endotoxin-Stimulated Primary Glial Cultures

1998 • 709 citations

Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pressure Stopped-Flow Technique, and Pulse Radiolysis

1997 • 620 citations

Accelerated reaction of nitric oxide with O ₂ within the hydrophobic interior of biological membranes

1998 • 590 citations

γ-Tocopherol traps mutagenic electrophiles such as NO _x and complements α-tocopherol: Physiological implications

1997 • 533 citations

Electrochemical Analysis of Protein Nitrotyrosine and Dityrosine in the Alzheimer Brain Indicates Region-Specific Accumulation

1998 • 507 citations

Rapid reaction between peroxonitrite ion and carbon dioxide: Implications for biological activity

1995 • 506 citations

A Molecular Redox Switch on p21

1997 • 488 citations

Reactive Nitrogen Intermediates Promote Low Density Lipoprotein Oxidation in Human Atherosclerotic Intima

1997 • 470 citations

Nitric oxide as an antioxidant

1991 • 441 citations

Formation of Nitrating and Chlorinating Species by Reaction of Nitrite with Hypochlorous Acid

1996 • 440 citations

Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils

1994 • 369 citations

Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras

1995 • 367 citations

Kinetics of Nitrosation of Thiols by Nitric Oxide in the Presence of Oxygen

1995 • 364 citations

Modulation of Superoxide-dependent Oxidation and Hydroxylation Reactions by Nitric Oxide

1996 • 355 citations

Why nitric oxide?

1992 • 350 citations

The basic chemistry of nitrogen monoxide and peroxynitrite

1998 • 345 citations

Differential Activation of Mitogen-activated Protein Kinases by Nitric Oxide-related Species

1996 • 332 citations

Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.

1995 • 326 citations

Carbon Dioxide Enhancement of Peroxynitrite-Mediated Protein Tyrosine Nitration

1996 • 302 citations

Reactions between Nitric Oxide, Superoxide, and Peroxynitrite: Footprints of Peroxynitrite in Vivo

1995 • 295 citations

Oxidation of thiols by nitric oxide and nitrogen dioxide: synthetic utility and toxicological implications

1982 • 288 citations

Nitration of Unsaturated Fatty Acids by Nitric Oxide-Derived Reactive Nitrogen Species Peroxynitrite, Nitrous Acid, Nitrogen Dioxide, and Nitronium Ion

1998 • 281 citations

Nitric Oxide Regulation of Tissue Free Radical Injury

1996 • 278 citations

Nitrite and Nitrate Analyses: A Clinical Biochemistry Perspective

1998 • 261 citations

Inflammation and NO_x-induced nitration: Assay for 3-nitrotyrosine by HPLC with electrochemical detection

1997 • 175 citations

Inhibition of Constitutive and Inducible Nitric Oxide Synthase: Potential Selective Inhibition

1995 • 157 citations

Nitration and Hydroxylation of Phenolic Compounds by Peroxynitrite

1996 • 148 citations

[39] Immunohistochemical methods to detect nitrotyrosine

1999 • 140 citations

Nitrotyrosine in plasma of celiac disease patients as detected by a new sandwich ELISA

1998 • 137 citations

Analytical Methods for 3-Nitrotyrosine as a Marker of Exposure to Reactive Nitrogen Species: A Review

1998 • 136 citations

Heme-dependent activation of soluble guanylate cyclase by nitric oxide: regulation of enzyme activity by porphyrins and metalloporphyrins.

1989 • 128 citations

Nitric Oxide and cGMP Signaling

1995 • 124 citations

Cytokine‐induced expression of an inducible type of nitric oxide synthase gene in cultured vascular smooth muscle cells

1993 • 117 citations

Monitoring Reactions of Nitric Oxide with Peptides and Proteins by Electrospray Ionization-Mass Spectrometry

1995 • 113 citations

Crystal Structure of the S-Nitroso Form of Liganded Human Hemoglobin^,

1998 • 107 citations

The Importance of Superoxide in Nitric Oxide-Dependent Toxicity

1996 • 105 citations

Products of γ-tocopherol reaction with NO2 and their formation in rat insulinoma (RINm5F) cells

1995 • 101 citations

Induction of Superoxide Anion and Nitric Oxide Production in Cultured Microglia^a

1994 • 94 citations

Can ONOOH Undergo Homolysis?

1998 • 94 citations

Quantitation of Protein-Bound 3-Nitrotyrosine and 3,4-Dihydroxyphenylalanine by High-Performance Liquid Chromatography with Electrochemical Array Detection

1997 • 88 citations

Isotope Dilution Mass Spectrometric Quantification of 3-Nitrotyrosine in Proteins and Tissues Is Facilitated by Reduction to 3-Aminotyrosine

1998 • 87 citations

Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362.

1995 • 83 citations

Analysis of 3-Nitrotyrosine in Biological Fluids and Protein Hydrolyzates by High-Performance Liquid Chromatography Using a Postseparation, On-line Reduction Column and Electrochemical Detection: Results with Various Nitrating Agents

1999 • 74 citations

Vitamin E concentrations in human blood plasma and platelets

1983 • 73 citations

Oxygen Radical-Nitric Oxide Reactions in Vascular Diseases

1995 • 72 citations

Characterisation of S‐nitrosohaemoglobin by mass spectrometry

1997 • 70 citations

The Effect of α-Tocopherol on the Nitration of γ-Tocopherol by Peroxynitrite

1999 • 69 citations

Nitration of tyrosyl-residues from extra- and intracellular proteins in human whole blood

1995 • 68 citations

Radical Nature of Peroxynitrite Reactivity

1998 • 62 citations

Neuroprotective and Neurodestructive Effects of Nitric Oxide and Redox Congeners

1994 • 61 citations

[4] Quantitation of protein-bound 3-nitrotyrosine by high-performance liquid chromatography with electrochemical detection

1999 • 45 citations

S-Nitrosothiols: Chemistry, Biochemistry, and Biological Actions

1995 • 40 citations

Determination of Biological Oxidative Stress Using High Performance Liquid Chromatography with Electrochemical Detection (HPLC-ECD)

1999 • 37 citations

Nomenclature of Tocopherols and Related Compounds

2016 • 30 citations

Nitric Oxide and Derived Species as Toxic Agents in Stroke, AIDS Dementia, and Chronic Neurodegenerative Disorders

1997 • 27 citations