Neural Stem Cells Spontaneously Express Dopaminergic Traits after Transplantation into the Intact or 6-Hydroxydopamine-Lesioned Rat

Induction of Midbrain Dopaminergic Neurons from ES Cells by Stromal Cell–Derived Inducing Activity

2000 • 1,267 citations

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

2002 • 1,179 citations

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

1996 • 1,027 citations

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

1995 • 1,014 citations

Cell replacement therapies for central nervous system disorders

2000 • 948 citations

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

1992 • 928 citations

Engraftable human neural stem cells respond to development cues, replace neurons, and express foreign genes

1998 • 776 citations

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

1999 • 545 citations

In Vitro Expansion of a Multipotent Population of Human Neural Progenitor Cells

1999 • 501 citations

Neural progenitor cell engraftment corrects lysosomal storage throughout the MRS VII mouse brain

1995 • 475 citations

Long-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease

1997 • 449 citations

Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex

1997 • 439 citations

“Global” cell replacement is feasible via neural stem cell transplantation: Evidence from the dysmyelinated shiverer mouse brain

1999 • 394 citations

Establishment and characterization of multipotent neural cell lines using retrovirus vector‐mediated oncogene transfer

1990 • 375 citations

Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes

1999 • 373 citations

Differentiation of Mesencephalic Progenitor Cells into Dopaminergic Neurons by Cytokines

1998 • 298 citations

Reactive astrocytes express the embryonic intermediate neurofilament nestin

1994 • 253 citations

Establishment and Properties of a Growth Factor-Dependent, Perpetual Neural Stem Cell Line from the Human CNS

2000 • 234 citations

Immortalized neural progenitor cells for CNS gene transfer and repair

1997 • 216 citations

Re-expression of the intermediate filament nestin in reactive astrocytes

1995 • 214 citations

Blastula-Stage Stem Cells Can Differentiate into Dopaminergic and Serotonergic Neurons after Transplantation

1998 • 201 citations

Adult Nestin‐expressing Subependymal Cells Differentiate to Astrocytes in Response to Brain Injury

1997 • 178 citations

A Clonal Line of Mesencephalic Progenitor Cells Converted to Dopamine Neurons by Hematopoietic Cytokines: A Source of Cells for Transplantation in Parkinson's Disease

2001 • 144 citations

FGF and EGF are mitogens for immortalized neural progenitors

1994 • 143 citations

Putting Stem Cells to Work

1999 • 130 citations

Mesencephalic Neural Stem (Progenitor) Cells Develop to Dopaminergic Neurons More Strongly in Dopamine-Depleted Striatum than in Intact Striatum

2000 • 101 citations

Synergy between growth factors and transmitters required for catecholamine differentiation in brain neurons

1995 • 87 citations

Long-term integration and neuronal differentiation of human embryonal carcinoma cells (NT era-2) transplanted into the caudoputamen of nude mice

1996 • 83 citations

Conditioned Medium from Activated Microglia Promotes Cholinergic Differentiation in the Basal Forebrainin Vitro

1996 • 52 citations

Cholinergic expression by a neural stem cell line grafted to the adult medial septum/diagonal band complex

2000 • 50 citations

Macrophage Cell-Conditioned Medium Promotes Cholinergic Differentiation of Undifferentiated Progenitors and Synergizes with Nerve Growth Factor Action in the Developing Basal Forebrain

2000 • 37 citations

Sonic Hedgehog Facilitates Dopamine Differentiation in the Presence of a Mesencephalic Glial Cell Line

2001 • 28 citations

Dopamine differentiation factors produce partial motor recovery in 6-hydroxydopamine lesioned rats

1995 • 27 citations