Helicobacter pylori factors associated with disease

The complete genome sequence of the gastric pathogen Helicobacter pylori

1997 • 3,529 citations

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

1999 • 1,904 citations

cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

1996 • 1,883 citations

Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.

1995 • 1,613 citations

Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori

1995 • 1,551 citations

Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.

1993 • 1,262 citations

Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging

1998 • 1,182 citations

Helicobacter pylori

1997 • 1,044 citations

Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection.

1997 • 962 citations

DNA diversity among clinical isolates ofHelicobacter pyloridetected by PCR-based RAPD fingerprinting

1992 • 760 citations

Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production

1993 • 671 citations

Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori

1998 • 618 citations

Helicobacter pylori and Atrophic Gastritis: Importance of the cagA Status

1995 • 601 citations

Free recombination within Helicobacter pylori

1998 • 591 citations

An inverse relation between cagA+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma.

1998 • 534 citations

Bactericidal and bacteriolytic activity of serum against gram-negative bacteria

1983 • 441 citations

The seroprevalence of cagA-positive Helicobacter pylori strains in the spectrum of gastroesophageal reflux disease

1998 • 390 citations

Hypothesis: The Changing Relationships ofHelicobacter pyloriand Humans: Implications for Health and Disease

1999 • 327 citations

Helicobacter pylori Infection and the Risk for Duodenal and Gastric Ulceration

1994 • 318 citations

Serologic detection of infection with cagA+ Helicobacter pylori strains

1995 • 295 citations

Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome.

1998 • 280 citations

Ecology of Helicobacter pylori in the human stomach.

1997 • 257 citations

Emergence of recombinant strains ofHelicobacter pyloriduring human infection

1999 • 238 citations

PCR-based subtractive hybridization and differences in gene content among strains of Helicobacter pylori

1998 • 232 citations

Typing of Helicobacter pylori vacA Gene and Detection of cagA Gene by PCR and Reverse Hybridization

1998 • 206 citations

The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity

1998 • 186 citations

Bactericidal and bacteriolytic activity of serum against gram-negative bacteria.

1983 • 177 citations

Prevalence of Vacuolating Cytotoxin Production and Distribution of Distinct vacA Alleles in Helicobacter pylori from China

1998 • 157 citations

Heterogeneous Helicobacter pylori isolates from members of a family with a history of peptic ulcer disease

1996 • 138 citations

Molecular genetic basis for the variable expression of Lewis Y antigen in Helicobacter pylori : analysis of the α(1,2) fucosyltransferase gene

1999 • 133 citations

Phenotypic diversity in Lewis expression of Helicobacter pylori isolates from the same host

1999 • 76 citations

High frequency of CagA+Helicobacter pylori infection in high-grade gastric MALT B-cell lymphomas

1998 • 60 citations

Role ofHelicobacter pylori cagA+ strains and specific host immune responses on the development of premalignant and malignant lesions in the gastric cardia

1999 • 59 citations

Isolation of a Helicobacter pylori protein, FldA, associated with mucosa-associated lymphoid tissue lymphoma of the stomach

1999 • 52 citations

Risk for Gastric Lymphoma in Persons with CagA+and CagA‐Helicobacter pyloriInfection

1997 • 29 citations