Characterization of poultry egg-white avidins and their potential as a tool in pretargeting cancer treatment

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1997 • 38,984 citations

Molecular Evolution and Phylogenetics

2000 • 7,148 citations

MEGA2: molecular evolutionary genetics analysis software

2001 • 6,215 citations

Phylogeny and Classification of the Birds

1991 • 1,797 citations

Avidin

1975 • 1,425 citations

[5] Avidin and streptavidin

1990 • 1,005 citations

Three-dimensional structures of avidin and the avidin-biotin complex.

1993 • 637 citations

Delivery of peptides and proteins through the blood–brain barrier

2001 • 450 citations

[2] Introduction to avidin-biotin technology

1990 • 424 citations

Study of strong to ultratight protein interactions using differential scanning calorimetry

1990 • 405 citations

Investigations of avidin and biotin for imaging applications.

1987 • 405 citations

Antibody-guided three-step therapy for high grade glioma with yttrium-90 biotin

1999 • 211 citations

Phase II trial of yttrium-90-DOTA-biotin pretargeted by NR-LU-10 antibody/streptavidin in patients with metastatic colon cancer.

2000 • 208 citations

Pretargeted adjuvant radioimmunotherapy with Yttrium-90-biotin in malignant glioma patients: A pilot study

2002 • 163 citations

Biochemical modifications of avidin improve pharmacokinetics and biodistribution, and reduce immunogenicity

1998 • 121 citations

Clinical experience with rhenium-186-labeled monoclonal antibodies for radioimmunotherapy: results of phase I trials.

1992 • 119 citations

Monoclonal antibody pretargetting techniques for tumour localization

1991 • 112 citations

Recombinant NeutraLite Avidin: a non‐glycosylated, acidic mutant of chicken avidin that exhibits high affinity for biotin and low non‐specific binding properties

2000 • 107 citations

Avidin–biotin system for delivery of diagnostic agents

1999 • 105 citations

Pretargeting radioimmunotherapy of a murine model of adult T-cell leukemia with the α-emitting radionuclide, bismuth 213

2002 • 104 citations

Sodium dodecyl sulfate‐polyacrylamide gel electrophoretic method for assessing the quaternary state and comparative thermostability of avidin and streptavidin

1996 • 103 citations

An Antibody-Avidin Fusion Protein Specific for the Transferrin Receptor Serves as a Delivery Vehicle for Effective Brain Targeting: Initial Applications in Anti-HIV Antisense Drug Delivery to the Brain

1999 • 97 citations

Tissue distribution of avidin and streptavidin injected to mice

1990 • 89 citations

Pretargeted radioimmunotherapy (PRIT™) for treatment of non-Hodgkin's lymphoma (NHL)

2001 • 74 citations

Rational Design of an Active Avidin Monomer

2003 • 72 citations

Reduced antibody response to streptavidin through site‐directed mutagenesis

2001 • 69 citations

Mutation of a critical tryptophan to lysine in avidin or streptavidin may explain why sea urchin fibropellin adopts an avidin‐like domain

1999 • 58 citations

Biotin Induces Tetramerization of a Recombinant Monomeric Avidin

2001 • 57 citations

Pharmacokinetic comparison of direct antibody targeting with pretargeting protocols based on streptavidin-biotin binding.

1995 • 53 citations

Chicken avidin-related proteins show altered biotin-binding and physico-chemical properties as compared with avidin

2002 • 53 citations

Limited proteolysis of native proteins: The interaction between avidin and proteinase K

1995 • 51 citations

Pharmacokinetics and biodistribution of radiolabeled avidin, streptavidin and biotin

1993 • 50 citations

The relationship of glycosylation and isoelectric point with tumor accumulation of avidin.

1999 • 47 citations

OCCURRENCE OF AVIDIN IN THE OVIDUCT AND SECRETIONS OF THE GENITAL TRACT OF SEVERAL SPECIES

1942 • 46 citations

Pretargeting strategies for radio-immunoguided tumour localisation and therapy

1997 • 45 citations

Engineering of chicken avidin: a progressive series of reduced charge mutants

1998 • 43 citations

Biochemical modification of streptavidin and avidin: in vitro and in vivo analysis.

1996 • 41 citations

Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli

1998 • 40 citations

Blood clearance of radiolabeled antibody: enhancement by lactosamination and treatment with biotin-avidin or anti-mouse IgG antibodies.

1988 • 37 citations

Enhancing the Thermal Stability of Avidin

2003 • 36 citations

Biotin-binding proteins in eggs of oviparous vertebrates

1981 • 36 citations

Mutation of the important Tyr-33 residue of chicken avidin: functional and structural consequences

2003 • 35 citations

Galactosylated streptavidin for improved clearance of biotinylated intact and F(ab')2 fragments of an anti-tumour antibody

1995 • 34 citations

Antibody-dependent signal amplification in tumor xenografts after pretreatment with biotinylated monoclonal antibody and avidin or streptavidin.

1996 • 27 citations

A radioimmunoassay for chicken avidin. Comparison with a [14C]biotin-binding method

1978 • 26 citations

The distribution of avidin

1962 • 21 citations

Mapping the common antigenic determinants in avidin and streptavidin

1997 • 19 citations

Reduction of streptavidin RYDS-mediated renal adhesion by site-directed mutagenesis

2002 • 11 citations

[53] A radioimmunoassay for chicken avidin

1979 • 10 citations

Production of monoclonal antibodies against avidin

1985 • 8 citations