Transformation of an arachidonic acid hydroperoxide into epoxyhydroxy and trihydroxy fatty acids by liver microsomal cytochrome P-450

Methods in Enzymology , Vol

1966 • 26,261 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

The mechanism of NADPH-dependent lipid peroxidation. The propagation of lipid peroxidation.

1979 • 390 citations

Preparation and purification of lipid hydroperoxides from arachidonic and γ‐linolenic acids

1976 • 216 citations

Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme.

1985 • 194 citations

The reaction of arachidonic acid epoxides (epoxyeicosatrienoic acids) with a cytosolic epoxide hydrolase

1983 • 190 citations

Preparation and assay of monohydroxy-eicosatetraenoic acids

1980 • 173 citations

Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties.

1981 • 165 citations

THE ROLE OF SUPEROXIDE AND SINGLET OXYGEN IN LIPID PEROXIDATION

1978 • 163 citations

Preparation and purification of arachidonic acid hydroperoxides of biological importance

1979 • 161 citations

Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid

1982 • 147 citations

The leukotrienes: a major step in the understanding of immediate hypersensitivity reactions

1981 • 142 citations

Imidazole antimycotics: Inhibitors of steroid aromatase

1985 • 137 citations

The oxidative metabolism of arachidonic acid by purified cytochromes P-450

1981 • 133 citations

Ketoconazole: a potent inhibitor of cytochrome P-450-dependent drug metabolism in rat liver.

1984 • 123 citations

Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets

1984 • 113 citations

Inhibition of rat liver microsomal cytochrome P-450 steroid hydroxylase reactions by imidazole antimycotic agents

1986 • 107 citations

Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4.

1985 • 95 citations

Endogenous release of hepoxilin A3 from isolated perifused pancreatic islets of Langerhans

1985 • 51 citations

Absolute configuration of epoxyeicosatrienoic acids (EETs) formed during catalytic oxygenation of arachidonic acid by purified rat liver microsomal cytochrome P-450

1984 • 48 citations

Hepoxilin A, hydroxyepoxide metabolite of arachidonic acid, stimulates transport of ⁴⁵Ca across the guinea pig visceral yolk sac

1984 • 46 citations

The mechanistic plurality of cytochrome P-450 and its biological ramifications

1984 • 45 citations

Interaction of cytochrome P-450 with a hydroperoxide derived from butylated hydroxytoluene. Mechanism of isomerization.

1985 • 35 citations

Cytochrome P-450 mediated interaction between hydroperoxide and molecular oxygen

1983 • 11 citations