Prognostic significance of proliferative and apoptotic markers in oral tongue squamous cell carcinomas

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

1983 • 2,745 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

Monoclonal antibodies against recombinant parts of the Ki‐67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave‐processed formalin‐fixed paraffin sections

1992 • 1,484 citations

Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level

1986 • 1,016 citations

Nucleolar organizer regions in lymphomas

1987 • 569 citations

Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma.

1995 • 477 citations

Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: relationship between p53 gene mutation and bcl-2/bax proteins in drug resistance.

1996 • 278 citations

Bcl-2 and Bcl-2-Related Proteins in Apoptosis Regulation

1995 • 210 citations

Proliferation index as a prognostic marker in breast cancer

1993 • 181 citations

Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis

1996 • 170 citations

Correlation of Tumor Markers p53, bcl-2, CD34, CD44H, CD44v6, and Ki-67 With Survival and Metastasis in Laryngeal Squamous Cell Carcinoma

1996 • 155 citations

Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival

1996 • 109 citations

Association of bcl-2, bax, bcl-xL and interleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia.

1996 • 92 citations

Predicting Recurrence and Survival in Patients with Laryngeal Cancer by Means of DNA Cytometry, Tumor Front Grading, and Proliferation Markers

1995 • 87 citations

Differential Expression of Apoptosis-Associated Genes baxand bcl-2 in Ovarian Cancer

2003 • 78 citations

Determination of Proliferation Index with MIB-1 in Advanced Ovarian Cancer Using Quantitative Image Analysis

1994 • 61 citations

Prognostic implication of proliferative markers MIB-1 and PC10 in esophageal squamous cell carcinoma

1996 • 59 citations

Diagnostic and prognostic value of nucleolar organizer regions in normal epithelium, dysplasia, and squamous cell carcinoma of the oral cavity

1997 • 52 citations

A re-evaluation of the relationships between the fibrillar centres and the nucleolus-organizing regions in reticulated nucleoli: ultrastructural organization, number and distribution of the fibrillar centres in the nucleolus of the mouse sertoli cell

1982 • 35 citations

Bax expression has prognostic significance that is enhanced when combined with AgNOR counts in glottic carcinomas

1998 • 34 citations

Diagnostic and prognostic value of nucleolar organizer regions in normal epithelium, dysplasia, and squamous cell carcinoma of the oral cavity

1997 • 34 citations

Expression of silver‐stained nucleolar organizer regions is coupled to cell cycle in rat thymic cells

1993 • 28 citations

Prognostic Significance of Nucleolar Organizer Regions in Adenoid Cystic Carcinomas of the Head and Neck

1997 • 24 citations

Correlation of two AgNOR counts with Ki‐67 labeling index: A study in fine‐needle aspirates of lymphoproliferative disorders and breast carcinoma

1994 • 18 citations

Nucleolar organizer regions and prognosis in glottic squamous cell carcinoma

1997 • 11 citations

Lack of prognostic significance for p53-overexpression and Ki-67-immunoreactivity in oral T1-2 squamous cell carcinomas

1997 • 4 citations