Diagnosis of Sickle Cell Anemia and β-Thalassemia with Enzymatically Amplified DNA and Nonradioactive Allele-Specific Oligonucleotide Probes

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Genomic sequencing.

1984 • 8,343 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

1986 • 1,863 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

DNA typing from single hairs

1988 • 809 citations

Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides.

1983 • 536 citations

The Molecular Genetics of Human Hemoglobin

1984 • 420 citations

THE MUTATION AND POLYMORPHISM OF THE HUMAN β-GLOBIN GENE AND ITS SURROUNDING DNA

1984 • 404 citations

Molecular characterization of seven beta-thalassemia mutations in Asian Indians.

1984 • 209 citations

Prenatal Diagnosis of β-Thalassemia

1983 • 193 citations

Chemical synthesis of oligonucleotides containing a free sulphydryl group and subsequent attachment of thiol specific probes

1985 • 169 citations

Quantification of the close association between DNA haplotypes and specific β-thalassaemia mutations in Mediterraneans

1984 • 149 citations

Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis.

1983 • 136 citations

The molecular basis of beta-thalassemia in Lebanon: application to prenatal diagnosis

1987 • 99 citations

The molecular basis of beta-thalassemia in Lebanon: application to prenatal diagnosis

1987 • 95 citations

Determination of the spectrum of beta-thalassemia genes in Spain by use of dot-blot analysis of amplified beta-globin DNA.

1988 • 83 citations

PRENATAL DIAGNOSIS OF BETA-THALASSAEMIA WITH THE SYNTHETIC-OLIGOMER TECHNIQUE

1985 • 81 citations

The spectrum of beta-thalassemia genes in China and Southeast Asia

1986 • 80 citations

Molecular basis of ? thalassemia in South China

1988 • 76 citations

Use of nonisotopic M13 probes for genetic analysis: application to HLA class II loci.

1986 • 59 citations

The spectrum of beta-thalassemia genes in China and Southeast Asia

1986 • 57 citations

Human beta-globin messenger RNA. I. Nucleotide sequences derived from complementary RNA.

1977 • 30 citations