Use of opioids to treat chronic, noncancer pain
Data up to Jan 2025
Total Citations Per Year
Abstract
References (99)
Clinical diagnosis of Alzheimer's disease
1984 • 27,279 citations
Mild Cognitive Impairment
1999 • 8,417 citations
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
1999 • 3,112 citations
A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease
1997 • 2,394 citations
Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence
1993 • 2,006 citations
Efficacy of multidisciplinary pain treatment centers: a meta-analytic review
1992 • 1,243 citations
Education and the prevalence of dementia and Alzheimer's disease
1993 • 1,154 citations
Management of cancer pain
1999 • 1,015 citations
Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain
1988 • 996 citations
Clinical trial of indomethacin in Alzheimer's disease
1993 • 996 citations
A Placebo-Controlled, Double-blind, Randomized Trial of an Extract of Ginkgo Biloba for Dementia
1997 • 973 citations
A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease
1997 • 965 citations
Social Disengagement and Incident Cognitive Decline in Community-Dwelling Elderly Persons
1999 • 932 citations
Estrogen Therapy in Postmenopausal Women
1998 • 927 citations
Painful neuropathy: altered central processing maintained dynamically by peripheral input
1992 • 770 citations
Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship
1997 • 769 citations
Comparison of Risperidone and Placebo for Psychosis and Behavioral Disturbances Associated With Dementia
1999 • 726 citations
Apolipoprotein E and Alzheimer disease.
1995 • 697 citations
Behavioral Treatment of Depression in Dementia Patients: A Controlled Clinical Trial
1997 • 656 citations
Opioid pseudoaddiction — an iatrogenic syndrome
1989 • 629 citations
A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia
1999 • 599 citations
The Effects of Donepezil in Alzheimer’s Disease – Results from a Multinational Trial<sup>1</sup>
1999 • 581 citations
The Efficacy of Ginkgo biloba on Cognitive Function in Alzheimer Disease
1998 • 579 citations
The nature of opioid responsiveness and its implications for neuropathic pain: new hypotheses derived from studies of opioid infusions
1990 • 574 citations
Opioid therapy for chronic nonmalignant pain: a review of the critical issues
1996 • 524 citations
Rivastigmine for Alzheimer's disease
2015 • 522 citations
The Management of Chronic Pain in Older Persons
1998 • 517 citations
Alzheimer's disease
1998 • 517 citations
Acute Pain Management: Operative or Medical Procedures and Trauma
1997 • 501 citations
Donepezil for dementia due to Alzheimer's disease
2003 • 500 citations
Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia
1991 • 494 citations
The Role of <EMPH TYPE="ITAL">APOE</EMPH> ∊4 in Modulating Effects of Other Risk Factors for Cognitive Decline in Elderly Persons
1999 • 454 citations
Randomised trial of oral morphine for chronic non-cancer pain
1996 • 395 citations
Proof of Efficacy of the Ginkgo Biloba Special Extract EGb 761 in Outpatients Suffering from Mild to Moderate Primary Degenerative Dementia of the Alzheimer Type or Multi-infarct Dementia
1996 • 377 citations
Long-term oral opioid therapy in patients with chronic nonmalignant pain
1992 • 368 citations
Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein.
1994 • 365 citations
Drug Abuse, Dependence, and Addiction in Chronic Pain Patients
1992 • 361 citations
Molecular biology of the opioid receptors: structures, functions and distributions
1995 • 345 citations
Long-term effects of continuous intrathecal opioid treatment in chronic pain of nonmalignant etiology
1996 • 344 citations
Prescription Opiate Abuse in Chronic Pain Patients: Clinical Criteria, Incidence, and Predictors
1997 • 312 citations
Opioid Therapy for Chronic Noncancer Back Pain
1998 • 311 citations
Controversies in the long-term management of analgesic therapy in patients with advanced cancer
1990 • 273 citations
Activity‐Dependent Changes in Rat Ventral Horn Neurons in vitro; Summation of Prolonged Afferent Evoked Postsynaptic Depolarizations Produce a D‐2‐Amino‐5‐Phosphonovaleric Acid Sensitive Windup
1990 • 270 citations
Exploring the Etiology of Alzheimer Disease Using Molecular Genetics
1997 • 260 citations
Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease
1996 • 250 citations
Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer’s disease: results of a placebo-controlled, double-blind, pilot study
1999 • 241 citations
Pain, depression, and illness behavior in a Pain Clinic population
1977 • 227 citations
Morphine differentially affects the sensory and affective pain ratings in neurogenic and idiopathic forms of pain
1991 • 209 citations
Morphine responsiveness of chronic pain: double-blind randomised crossover study with patient-controlled analgesia
1992 • 202 citations
Cholinesterase Inhibitors: A Therapeutic Strategy for Alzheimer Disease
1999 • 183 citations
A review of the effects of opioids on psychomotor and cognitive functioning in humans.
1995 • 180 citations
Intravenous Infusion of the NMDA Antagonist, Ketamine, in Chronic Posttraumatic Pain with Allodynia
1995 • 173 citations
What Factors Affect Physicians' Decisions to Prescribe Opioids for Chronic Noncancer Pain Patients?
1997 • 164 citations
Efficacy of controlled-release codeine in chronic non-malignant pain: a randomized, placebo-controlled clinical trial
1995 • 162 citations
Selegiline for Alzheimer's disease
2003 • 157 citations
Prolonged Treatment with Transdermal Fentanyl in Neuropathic Pain
1998 • 147 citations
Medication misuse, abuse and dependence in chronic pain patients
1997 • 146 citations
Consequences of the 1989 New York State Triplicate Benzodiazepine Prescription Regulations
1991 • 145 citations
Evaluation and Treatment of Chronic Pain.
1985 • 141 citations
The APOE ∍4 allele Is Associated with Decline on Delayed Recall Performance in Community‐Dwelling Older Adults
1998 • 127 citations
Opioid analgesics in the treatment of chronic intractable pain of non-neoplastic origin
1984 • 126 citations
Outcome of Chronic Opioid Therapy for Non-Cancer Pain
1998 • 126 citations
Mechanisms of Neurotoxicity Associated with Amyloid β Deposition and the Role of Free Radicals in the Pathogenesis of Alzheimer's Disease: A Critical Appraisal
1997 • 125 citations
Codeine plus paracetamol versus paracetamol in longer-term treatment of chronic pain due to osteoarthritis of the hip. A randomised, double-blind, multi-centre study
1990 • 125 citations
Narcotic Analgesics in Anesthesiology
1982 • 124 citations
The use of opioids for the treatment of chronic pain. A consensus statement from the American Academy of Pain Medicine and the American Pain Society.
1997 • 120 citations
Estrogen Stakes Claim to Cognition
1997 • 120 citations
JTP-4819: a novel prolyl endopeptidase inhibitor with potential as a cognitive enhancer.
1995 • 117 citations
Long-term use of narcotic analgesics in chronic pain
1984 • 111 citations
Codeine and oxycodone use in patients with chronic rheumatic disease pain
1998 • 105 citations
Antioxidant and Prooxidant Actions of Estrogens: Potential Physiological and Clinical Implications
1998 • 95 citations
Opioid sensitivity of chronic pain: a patient‐controlled analgesia method
1992 • 93 citations
Prolonged morphine self-administration and addiction liability. Evaluation of two theories in a bone marrow transplant unit
1989 • 88 citations
Apolipoprotein E4, cholinergic integrity and the pharmacogenetics of Alzheimer’s disease
1998 • 83 citations
Tacrine for Alzheimer's disease
1999 • 81 citations
Support for carers of people with Alzheimer's type dementia
1998 • 78 citations
Clinicians' attitudes about prolonged use of opioids and the issue of patient heterogeneity
1996 • 69 citations
The National Institute on Aging/Alzheimer's Association Recommendations on the Application of Apolipoprotein E Genotyping to Alzheimer's Diseasea
1996 • 67 citations
The use of oral opioids in patients witt chronic non‐cancer pain
1997 • 66 citations
Chronic pain exacerbated by long-term narcotic use in patients with nonmalignant disease: clinical syndrome and treatment.
1978 • 59 citations
Substance dependence and chronic pain: Profile of 50 patients treated in an alcohol and drug dependence unit
1986 • 52 citations
Practice guidelines for chronic pain management. A report by the American Society of Anesthesiologists Task Force on Pain Management, Chronic Pain Section.
1997 • 49 citations
A Pilot Study of Prednisone in Alzheimer's Disease
1996 • 48 citations
Strategies That Support Declining Cholinergic Neurotransmission in Alzheimer’s Disease Patients
1999 • 40 citations
Treatment of Alzheimer’s Disease: Current Approaches and Promising Developments
1998 • 38 citations
Clinical practice guidelines for chronic non-malignant pain syndrome patients
1995 • 37 citations
Comprehensive pretreatment and outcome assessment for chronic opioid therapy in nonmalignant pain
1996 • 35 citations
Prognostic variability among chronic pain patients: implications for study design, interpretation, and reporting.
1988 • 35 citations
Prescription Drug Diversion Control and Medical Practice
1992 • 33 citations
The need for an open mind about the treatment of chronic nonmalignant pain
1994 • 27 citations
Epidemiology of Alzheimer’s Disease: From Gene to Prevention
1999 • 26 citations
Guidelines for managing chronic non-malignant pain. Opioids and other agents. College of Physicians and Surgeons of Alberta.
1995 • 25 citations
New therapeutic approaches to cognitive impairment.
1998 • 24 citations
Opioids in the treatment of chronic pain of nonmalignant origin.
1991 • 16 citations
The Epidemiology of Alzheimer’s Disease: The Role of Estrogen in Reducing Risk
1999 • 7 citations
Inflammation, Anti-Inflammatory Drugs and Alzheimer’s Disease
1999 • 4 citations
Predicting Who Will Develop Alzheimer’s Disease
1999 • 3 citations
MSV House of Delegates passes opioid guidelines. Medical Society of Virginia Pain Management Subcommittee.
1998 • 1 citations
Deleted Work
1955 • 0 citations