Macrophages and antitumor reactions

The Macrophage as an Effector Cell

1980 • 628 citations

Macrophage content of tumours in relation to metastatic spread and host immune reaction

1974 • 380 citations

Cooperation of Immune Lymphoid Cells with Macrophages in Tumour Immunity

1970 • 315 citations

IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.

1982 • 285 citations

Macrophage-mediated tumor cell killing: regulation of expression of cytolytic activity by prostaglandin E.

1981 • 238 citations

Role of Basophils, Mast Cells, and Vasoamines in Hypersensitivity Reactions with a Delayed Time Course (Part 1 of 4)

1977 • 201 citations

Polypeptide-Binding Membrane Receptors: Analysis and Classification

1981 • 195 citations

Langerhans Cells as Macrophages in Skin and Lymhphoid Organs

1980 • 195 citations

Antiinflammatory Effects of Murine Malignant Cells

1974 • 183 citations

Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide.

1982 • 168 citations

T cell-dependent mast cell degranulation and release of serotonin in murine delayed-type hypersensitivity.

1980 • 162 citations

Participation of lymphocyte activating factor (Interleukin 1) in the induction of cytotoxic T cell responses.

1980 • 157 citations

Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event.

1981 • 153 citations

Secretion of Macrophage Enzymes in Relation to the Pathogenesis of Chronic Inflammation

1976 • 144 citations

The role of macrophages in the generation of T-helper cells

1975 • 139 citations

Macrophage Activation for Tumor Cytotoxicity: Increased Lymphokine Responsiveness of Peritoneal Macrophages During Acute Inflammation

1978 • 137 citations

Effects of Neoplasms on Inflammation: Depression of Macrophage Accumulation after Tumor Implantation

1976 • 137 citations

Role of macrophages in tumour immunity. I. Co-operation between macrophages and lymphoid cells in syngeneic tumour immunity.

1972 • 126 citations

Effects on in vitro tumor growth of murine macrophages isolated from sarcoma lines differing in immunogenicity and metastasizing capacity

1978 • 126 citations

Macrophage-T Cell Interactions Involving Listeria Monocytogenes—Role of the H-2 Gene Complex

1979 • 113 citations

Studies on the purification and structure-function relationships of murine lymphocyte activating factor (interleukin 1)

1980 • 103 citations

Macrophage content of metastatic and nonmetastatic rodent neoplasms.

1981 • 94 citations

Heterogeneity of mononuclear phagocytes

1981 • 92 citations

Immunosuppressor cells from newborn mouse spleen are macrophages differentiating in vitro from monoblastic precursors

1981 • 64 citations

Possible Evidence for Antibody-Dependent Macrophage-Mediated Cytotoxicity Directed against Murine Adenocarcinoma Cells in Vivo

1976 • 64 citations

Mechanisms of target recognition and destruction in macrophage-mediated tumor cytotoxicity.

1982 • 62 citations

Macrophage requirement for growth of a murine fibrosarcoma

1978 • 60 citations

On the origin and mode of action of functionally distinct macrophage subpopulations

1980 • 60 citations

Adherent Cell Function in Murine T Lymphocyte Antigen Recognition. I. A Macrophage-Dependent T Cell Proliferation Assay in the Mouse

1978 • 59 citations

Macrophage content and immunogenicity of C57BL/6J and BALB/cByJ methylcholanthrene‐induced sarcomas

1980 • 54 citations

CYTOTOXICITY OF MURINE PERITONEAL MACROPHAGES IN TUMOUR ALLOGRAFT IMMUNITY

1972 • 49 citations

Macrophage activation for tumor cytotoxicity: regulatory mechanisms for induction and control of cytotoxic activity.

1982 • 48 citations

Characterization of macrophage subpopulations responsive to activation by endotoxin and lymphokines.

1981 • 46 citations

Antigen-specific murine T-cell proliferation: Role of macrophage surface Ia and factors

1979 • 43 citations

The peritoneal antigen‐presenting macrophage: control and immunogenic properties of distinct subpopulations

1981 • 42 citations

Host cells in transplanted murine tumors and their possible relevance to tumor growth.

1979 • 40 citations

Macrophages as Regulators of Immune Responses Against Tumors

1980 • 38 citations

Regulation of lymphocyte proliferation and differentiation by macrophages.

1978 • 37 citations

Potentiation of macrophage tumor cytostasis by tumor-induced ascites.

1981 • 37 citations

Delayed-type hypersensitivity to allogeneic cells in mice. III. Sensitivity to cell-surface antigens coded by the major histocompatibility complex and by other genes.

1979 • 37 citations

Suppression of lymphokine production by macrophages infiltrating murine virus‐induced tumors

1979 • 36 citations

Indomethacin-mediated enhancement of lymphocyte response to mitogens in healthy subjects and lung cancer patients

1980 • 36 citations

Evidence for Mononuclear Phagocytes in Solid Neoplasms and Appraisal of Their Nonspecific Cytotoxic Capabilities

1980 • 34 citations

Delayed-type hypersensitivity induced by antigen pulsed, bone marrow-derived macrophages

1980 • 30 citations

Natural cytotoxic macrophages in the peritoneal cavity of mice

1979 • 28 citations

Indomethacin‐sensitive suppressor cells regulate the cell‐mediated cytotoxic response to SV 40‐induced tumor‐associated antigens in mice

1980 • 28 citations

Nonspecific “Lymphocyte Activating” Factors Produced by Macrophages

1979 • 28 citations

Role of macrophage in in vitro augmentation of rat, mouse, and human natural killer activities.

1981 • 27 citations

Enhancing and suppressive effects of macrophages on T-lymphocyte stimulation in vitro

1979 • 26 citations

The induction of lymphocytes with the capacity to render macrophages cytotoxic in an allogeneic murine system.

1982 • 26 citations

The role of a cytophilic factor from challenged immune peritoneal lymphocytes in specific macrophage cytotoxicity.

1974 • 26 citations

Inhibition of Contact Sensitivity by Macrophages

1981 • 25 citations

Enhanced PGE production by MAF-treated peritoneal exudate macrophages

1979 • 24 citations

Dual role for alveolar macrophages in humoral and cell-mediated immune responses: evidence for suppressor and enhancing functions.

1981 • 23 citations

Suppression of Antibody-Sensitized Tumor Cells by Macrophages: Insufficient Supply or Activation of Macrophages within Large Tumors

1979 • 23 citations

Distinct signals for antibody-dependent and nonspecific killing of tumor targets mediated by macrophages.

1982 • 21 citations

Brief Communication: In Vitro Activation of Armed Macrophages and the Therapeutic Application in Mice

1974 • 20 citations

Therapy with allogeneic immune peritoneal cells.

1974 • 19 citations

Effects of silica on macrophages and lymphocytes.

1977 • 19 citations

Tumor immunity in prognosis : the role of mononuclear cell infiltration

1982 • 18 citations

Macrophage-like suppressor cells in rats

1980 • 18 citations

Immunologic Factors Influencing the Intra-tumor Localization of ADCC Effector Cells

1978 • 17 citations

Promotion of fibrosarcoma cell growth by products of syngeneic host macrophages

1981 • 16 citations

Host macrophages are involved in systemic adoptive immunity against tumors

1982 • 15 citations

Interferon as a model lymphokine.

1981 • 12 citations

Nonspecific “lymphocyte activating” factors produced by macrophages

1979 • 11 citations

Induction of resistance or enhancement to a transplantable murine plasmacytoma by transfer of non-immune leucocytes

1976 • 10 citations

A small molecular weight peptide from P815 mastocytoma cells induces macrophage cytotoxicity

1981 • 9 citations

Destructino of Murine Lymphoma Cells by Allogeneic Periotoneal Macrophages In Vitro: Influence of Antiserum<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 8 citations

Concentration-dependent role of macrophages in mixed lymphocyte reaction regulation: elaboration of nondialyzable heat-stable inhibitor and heat-labile enhancing factors.

1979 • 7 citations

Promotion of L1210 Tumour Growth by Macrophages

1978 • 6 citations

Macrophage Tumor Cells Can Help to Cure Murine Lymphoma

1981 • 6 citations

Ia Antigens on Antigen‐presenting Cells do not Carry the Same Ia Specificities as Detected on Suppressor and Helper T Cells

1981 • 6 citations

Murine macrophage cytotoxicity induced by mastocytoma cells, cell-free mastocytoma exudates, and extracts

1981 • 5 citations

Serological analysis of macrophage surface alloantigens

1981 • 5 citations

Mechanism by which antibodies to non-AgB antigens mediate rejection of rat leukaemia cells

1980 • 2 citations