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The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal smooth muscle

Data up to Jan 2025

Published1989
Citations3
References20

Total Citations Per Year

Abstract

References (20)

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

1986 • 831 citations

The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea‐pig ileum longitudinal muscle strip

1969 • 698 citations

R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet.

1985 • 270 citations

Substance P induced hydrolysis of inositol phospholipids in guinea-pig ileum and rat hypothalamus

1983 • 181 citations

Phorbol ester effects on neurotransmission: interaction with neurotransmitters and calcium in smooth muscle.

1985 • 149 citations

Calcium in Muscle Activation

1988 • 136 citations

Tension responses of chemically skinned fibre bundles of the guinea‐pig taenia caeci under varied ionic environments

1981 • 96 citations

A diacylglycerol kinase inhibitor, R59022, potentiates secretion by and aggregation of thrombin-stimulated human platelets

1987 • 79 citations

Histamine‐induced inositol phospholipid breakdown in the longitudinal smooth muscle of guinea‐pig ileum

1985 • 61 citations

Calcium in muscle activation

1989 • 55 citations

Evidence for two distinct types of potassium-activated calcium channels in an intestinal smooth muscle.

1980 • 54 citations

Depolarisation of guinea-pig visceral smooth muscle causes hydrolysis of inositol phospholipids

1986 • 51 citations

Substance P can contract the longitudinal muscle of the guinea‐pig small intestine by releasing intracellular calcium

1984 • 40 citations

On the mechanism of contraction and desensitization induced by substance P in the intestinal muscle of the guinea‐pig.

1983 • 38 citations

Substance P action on phosphoinositides in guinea-pig intestinal muscle: a possible transduction mechanism?

1985 • 35 citations

Chloride removal selectively inhibits phasic contractions of guinea pig ileal longitudinal smooth muscle

1982 • 11 citations

Differential effects of phenylmethanesulfonyl fluoride (PMSF) on carbachol and potassium stimulated phosphoinositide turnover and contraction in longitudinal smooth muscle of guinea pig ileum

1984 • 7 citations

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The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal… (1989) – European Journal of Pharmacology | Metascience Observatory Explorer