Integrin Receptor GPIIb/IIIa Bound State Conformation of the Fibrinogen γ-Chain C-Terminal Peptide 400−411: NMR and Transfer NOE Studies

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

Investigation of exchange processes by two-dimensional NMR spectroscopy

1979 • 4,720 citations

Multiple quantum filters for elucidating NMR coupling networks

1982 • 1,780 citations

Circular dichroic analysis of protein conformation: Inclusion of the β-turns

1978 • 1,088 citations

FIBRINOGEN AND FIBRIN

1984 • 748 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Calculation of protein conformations by proton-proton distance constraints

1985 • 564 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

An Abnormal Platelet Glycoprotein Pattern in Three Cases of Glanzmann's Thrombasthenia

1974 • 445 citations

Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors.

1987 • 428 citations

Localization of an Arg-Gly-Asp Recognition Site Within an Integrin Adhesion Receptor

1988 • 402 citations

The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit.

1990 • 316 citations

Examination of the platelet membrane glycoprotein IIb-IIIa complex and its interaction with fibrinogen and other ligands by electron microscopy.

1992 • 309 citations

Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets

1991 • 289 citations

Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide

1991 • 221 citations

Inhibition of fibronectin binding to platelets by proteolytic fragments and synthetic peptides which support fibroblast adhesion.

1985 • 220 citations

A discrete sequence in a platelet integrin is involved in ligand recognition

1991 • 204 citations

tRNA _i ^met Functions in Directing the Scanning Ribosome to the Start Site of Translation

1988 • 199 citations

Cell-surface regulation of β1-integrin activity on developing retinal neurons

1991 • 191 citations

Studies of synthetic helical peptides using circular dichroism and nuclear magnetic resonance

1990 • 167 citations

Immobilized Arg-Gly-Asp (RGD) peptides of varying lengths as structural probes of the platelet glycoprotein IIb/IIIa receptor

1992 • 158 citations

Efficient surface expression of platelet GPIIb-IIIa requires both subunits

1989 • 158 citations

Binding of recombinant fibrinogen mutants to platelets.

1994 • 154 citations

Amino Acid Sequences in Fibrinogen Mediating Its Interaction with Its Platelet Receptor, GPIIbIIIa

1989 • 145 citations

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques.

1992 • 138 citations

The Two-Dimensional Transferred Nuclear Overhauser Effect: Theory and Practice

1993 • 134 citations

A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation.

1992 • 125 citations

Structure of platelet glycoprotein IIIa. A common subunit for two different membrane receptors.

1988 • 122 citations

Calibration of effective van der Waals atomic contact radii for proteins and peptides

1987 • 69 citations

Fibrinogen and fibrin: Biochemistry and pathophysiology

1986 • 63 citations

Further studies on the topography of human platelet glycoprotein IIb. Localization of monoclonal antibody epitopes and the putative glycoprotein IIIa- and fibrinogen-binding regions

1991 • 40 citations

Anti-idiotypic antibodies against an antibody to the platelet glycoprotein (GP) IIb-IIIa complex mimic GP IIb-IIIa by recognizing fibrinogen.

1992 • 35 citations

Design and Evaluation of Nonpeptide Fibrinogen .gamma. Chain-Based GPIIB/IIIA Antagonists

1995 • 34 citations

Evidence for novel binding sites on the platelet glycoprotein IIb and IIIa subunits and immobilized fibrinogen

1993 • 26 citations

Adamantane and Nipecotic Acid Derivatives as Novel β-Turn Mimics

1994 • 12 citations

Nuclear magnetic resonance

1976 • 9 citations