Cloning of AIP1, a Novel Protein That Associates with the Apoptosis-linked Gene ALG-2 in a Ca2+-dependent Reaction

Caspases: the executioners of apoptosis

1997 • 4,674 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

[31] Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands

1988 • 1,048 citations

Involvement of an ICE-like protease in Fas-mediated apoptosis

1995 • 757 citations

Defects in regulation of apoptosis in caspase-2-deficient mice

1998 • 688 citations

Calcium binding and conformational response in EF-hand proteins

1996 • 650 citations

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1995 • 616 citations

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.

1994 • 605 citations

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.

1994 • 596 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

Interfering with Apoptosis: Ca ²⁺ -Binding Protein ALG-2 and Alzheimer's Disease Gene ALG-3

1996 • 481 citations

Apoptosis Induced by Withdrawal of Trophic Factors Is Mediated by p38 Mitogen-activated Protein Kinase

1997 • 471 citations

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2

1997 • 368 citations

Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex.

1989 • 315 citations

Lymphocyte Apoptosis: Mediation by Increased Type 3 Inositol 1,4,5-Trisphosphate Receptor

1996 • 268 citations

Calcineurin functions in Ca(2+)-activated cell death in mammalian cells.

1995 • 260 citations

T Cells Deficient in Inositol 1,4,5-Trisphosphate Receptor Are Resistant to Apoptosis

1997 • 259 citations

Evidence for CPP32 Activation in the Absence of Apoptosis during T Lymphocyte Stimulation

1997 • 155 citations

Activation of caspase-3-like enzymes in non-apoptotic T cells

1998 • 105 citations

Portrait of an executioner: the molecular mechanism of Fas/APO-1-induced apoptosis

1997 • 100 citations

Characterization of the pH signal transduction pathway gene palA of Aspergillus nidulans and identification of possible homologs

1997 • 92 citations

Fas antigen-mediated DNA fragmentation and apoptotic morphologic changes are regulated by elevated cytosolic Ca2+ level.

1995 • 90 citations

In Vivo Calcium Elevations in Thymocytes with T Cell Receptors That Are Specific for Self Ligands

1992 • 72 citations

BRO1, a Novel Gene That Interacts with Components of the Pkc1p–Mitogen-Activated Protein Kinase Pathway in Saccharomyces cerevisiae

1996 • 67 citations

Dissociation of apoptosis and activation of IL-1beta-converting enzyme/Ced-3 proteases by ALG-2 and the truncated Alzheimer's gene ALG-3.

1997 • 62 citations

Functional cloning of genes involved in T-cell receptor-induced programmed cell death

1997 • 30 citations

Molecular cloning of a splice variant of Caenorhabditis elegans YNK1, a putative element in signal transduction

1997 • 13 citations