Heparin enhances thrombin-stimulated prostaglandin I2 production by cultured endothelial cells

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.

1982 • 434 citations

Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells.

1984 • 330 citations

Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells.

1987 • 281 citations

Effect of bradykinin and thrombin on prostacyclin synthesis in endothelial cells from calf and pig aorta and human umbilical cord vein

1980 • 249 citations

Dual role of interfacial phospholipid in phospholipase A2 catalysis.

1977 • 127 citations

Activation of heparin cofactor II by fibroblasts and vascular smooth muscle cells.

1987 • 97 citations

Snake Venoms and Blood Coagulation

1979 • 74 citations

Heparin and the atherosclerotic process.

1984 • 56 citations

Mechanism of thrombin binding to endothelial cells

1983 • 49 citations

Probing the role of substrate conformation in phospholipase A2 action on aggregated phospholipids using constrained phosphatidylcholine analogues.

1988 • 34 citations

Internalization and metabolism of endogenous heparin by cultured endothelial cells

1986 • 34 citations

Uncontrolled PGI2 production by whole vessel wall segments due to thrombin generation and its prevention by heparin

1979 • 26 citations

Release of heparan sulfate proteoglycans from cultured aortic endothelial cells by thrombin

1985 • 24 citations

Immediate effects of heparin and LMW heparin on some platelet and endothelial derived factors

1988 • 20 citations

Interaction of thrombin with heparin cofactor II and antithrombin III on prostacyclin production by cultured endothermal cells

1989 • 14 citations