Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

The Electrical Double Layer and the Theory of Electrocapillarity.

1947 • 2,993 citations

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

1984 • 1,339 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Conduction and selectivity in potassium channels

1983 • 665 citations

Divalent Ions and the Surface Potential of Charged Phospholipid Membranes

1971 • 643 citations

Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH

1975 • 599 citations

Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.

1984 • 513 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

The permeability of the endplate channel to organic cations in frog muscle.

1980 • 362 citations

Effect of Divalent Cations on Potassium Conductance of Squid Axons

1969 • 304 citations

Structure and function of an acetylcholine receptor

1982 • 281 citations

Quaternary structure of the acetylcholine receptor

1985 • 281 citations

A structural model of the acetylcholine receptor channel based on partition energy and helix packing calculations

1984 • 260 citations

The theory of ion transport through membrane channels

1985 • 208 citations

Structure and dynamics of ion transport through gramicidin A

1984 • 180 citations

Formation of ion channels by a negatively charged analog of gramicidin a

1977 • 160 citations

Interactions in cation permeation through the gramicidin channel. Cs, Rb, K, Na, Li, Tl, H, and effects of anion binding

1978 • 132 citations

Selectivity of cations and nonelectrolytes for acetylcholine-activated channels in cultured muscle cells.

1978 • 127 citations

An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions.

1985 • 104 citations

Fluctuations of barrier structure in ionic channels

1980 • 102 citations

Topological mapping of acetylcholine receptor: evidence for a model with five transmembrane segments and a cytoplasmic COOH-terminal peptide.

1985 • 101 citations

Mouse-Torpedo hybrid acetylcholine receptors: functional homology does not equal sequence homology.

1985 • 98 citations

Molecular dynamics study of ion transport in transmembrane protein channels

1981 • 66 citations

Comparison of Nernst-Planck and reaction rate models for multiply occupied channels.

1982 • 65 citations

Molecular dynamics simulation of cation motion in water-filled gramicidinlike pores

1984 • 60 citations

Strong electrolyte continuum theory solution for equilibrium profiles, diffusion limitation, and conductance in charged ion channels

1985 • 57 citations

Permeability of the endplate membrane activated by acetylcholine to some organic cations

1977 • 52 citations

Interactions of monovalent cations with sodium channels in squid axon. I. Modification of physiological inactivation gating.

1985 • 48 citations

Theory of transport noise in membrane channels with open-closed kinetics

1979 • 27 citations