Expression profiling of CD34 ⁺ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

2002 • 1,959 citations

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

2001 • 1,672 citations

CD34: structure, biology, and clinical utility [see comments]

1996 • 891 citations

Programmed cell death: Apoptosis and oncogenesis

1991 • 856 citations

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

2000 • 830 citations

CD34: structure, biology, and clinical utility [see comments]

1996 • 690 citations

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

1997 • 683 citations

Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

1996 • 650 citations

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

1995 • 582 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

2002 • 501 citations

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

1997 • 462 citations

STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells.

1994 • 459 citations

The balanced and the unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation

1994 • 361 citations

Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

1988 • 313 citations

Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells

1989 • 293 citations

Small changes in expression affect predisposition to tumorigenesis

2001 • 268 citations

Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia

2002 • 254 citations

Lack of Interferon Consensus Sequence Binding Protein (ICSBP) Transcripts in Human Myeloid Leukemias

1998 • 207 citations

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia.

1991 • 202 citations

Antimicrobial polypeptides of human neutrophils

1990 • 188 citations

The Secondary Leukemias: Challenges and Research Directions

1996 • 172 citations

THERAPY-RELATED MYELOID LEUKEMIA

1996 • 170 citations

Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family.

1994 • 167 citations

Identification of myelodysplastic syndrome–specific genes by DNA microarray analysis with purified hematopoietic stem cell fraction

2001 • 163 citations

Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter.

1992 • 163 citations

Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1–1.5 Mb and preparation of a PAC-based physical map

1997 • 154 citations

Antimicrobial polypeptides of human neutrophils

1990 • 152 citations

Class III receptor tyrosine kinases: role in leukaemogenesis

2002 • 128 citations

Identification of human eosinophil lysophospholipase as the constituent of Charcot-Leyden crystals.

1980 • 122 citations

Regulation of Apoptosis in Myeloid Cells by Interferon Consensus Sequence–Binding Protein

1999 • 119 citations

Platelet Factor 4 and Other CXC Chemokines Support the Survival of Normal Hematopoietic Cells and Reduce the Chemosensitivity of Cells to Cytotoxic Agents

1997 • 87 citations

Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4.

1991 • 52 citations

Establishment and characterization of a megakaryoblast cell line with amplification of MLL

1998 • 49 citations

Comprehensive genotypic analysis of leukemia: clinical and therapeutic implications

2002 • 49 citations

Genes for beta-thromboglobulin and platelet factor 4 are closely linked and form part of a cluster of related genes on chromosome 4

1992 • 38 citations

Genes for beta-thromboglobulin and platelet factor 4 are closely linked and form part of a cluster of related genes on chromosome 4

1992 • 29 citations