Tools for the diagnosis of hepatitis C virus infection and hepatic fibrosis staging

A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C

2003 • 4,023 citations

An algorithm for the grading of activity in chronic hepatitis C

1996 • 3,858 citations

Diagnosis, management, and treatment of hepatitis C: An update

2008 • 2,951 citations

Transient elastography: a new noninvasive method for assessment of hepatic fibrosis

2003 • 2,619 citations

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

2008 • 2,567 citations

Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence

2012 • 2,459 citations

Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C

2005 • 2,424 citations

Liver cirrhosis

2008 • 1,783 citations

Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

2005 • 1,538 citations

Performance of Transient Elastography for the Staging of Liver Fibrosis: A Meta-Analysis

2008 • 1,451 citations

Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study

2001 • 1,432 citations

Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study

2005 • 1,243 citations

Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C

2002 • 1,150 citations

An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases

2011 • 1,089 citations

Pitfalls of liver stiffness measurement: A 5-year prospective study of 13,369 examinations

2009 • 1,087 citations

Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model

2002 • 1,078 citations

EASL Clinical Practice Guidelines: Management of hepatitis C virus infection

2011 • 1,067 citations

Serum markers detect the presence of liver fibrosis: A cohort study

2004 • 1,039 citations

Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: An updated meta-analysis

2010 • 962 citations

Epidemiology and natural history of HCV infection

2013 • 955 citations

Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease

2007 • 837 citations

Unravelling hepatitis C virus replication from genome to function

2005 • 807 citations

Elastography for the diagnosis of severity of fibrosis in chronic liver disease: A meta-analysis of diagnostic accuracy

2010 • 668 citations

A novel panel of blood markers to assess the degree of liver fibrosis

2005 • 550 citations

Hepascore: An Accurate Validated Predictor of Liver Fibrosis in Chronic Hepatitis C Infection

2005 • 531 citations

Ultrasound-Based Transient Elastography for the Detection of Hepatic Fibrosis: Systematic Review and Meta-analysis

2007 • 513 citations

Ratio of Serum Aspartate to Alanine Aminotransferase in Chronic Hepatitis Relationship to Cirrhosis

1988 • 497 citations

Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients

2011 • 474 citations

Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C

2011 • 397 citations

Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients

2007 • 383 citations

FibroTest and FibroScan for the Prediction of Hepatitis C-Related Fibrosis: A Systematic Review of Diagnostic Test Accuracy

2007 • 362 citations

Evaluation of a panel of non-invasive serum markers to differentiate mild from moderate-to-advanced liver fibrosis in chronic hepatitis C patients

2004 • 330 citations

Meta-analyses of FibroTest diagnostic value in chronic liver disease

2007 • 315 citations

Use of Sequence Analysis of the NS5B Region for Routine Genotyping of Hepatitis C Virus with Reference to C/E1 and 5′ Untranslated Region Sequences

2007 • 288 citations

Circulating Matrix Metalloproteinases 1, 2, 9 and Their Inhibitors TIMP-1 and TIMP-2 as Serum Markers of Liver Fibrosis in Patients With Chronic Hepatitis C: Comparison With PIIINP and Hyaluronic Acid

2004 • 254 citations

Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches

2011 • 237 citations

Clinical utility of total HCV core antigen quantification: A new indirect marker of HCV replication

2002 • 220 citations

Development of a Simple and Highly Sensitive Enzyme Immunoassay for Hepatitis C Virus Core Antigen

1999 • 216 citations

A Meta-analysis of Transient Elastography for the Detection of Hepatic Fibrosis

2010 • 211 citations

Dynamics of viremia in early hepatitis C virus infection

2005 • 202 citations

SAFE biopsy: A validated method for large-scale staging of liver fibrosis in chronic hepatitis C

2009 • 183 citations

APASL consensus statements and management algorithms for hepatitis C virus infection

2012 • 165 citations

Nomenclature and Numbering of the Hepatitis C Virus

2009 • 149 citations

Accuracy of Rapid and Point-of-Care Screening Tests for Hepatitis C

2012 • 144 citations

A new sensitive and automated chemiluminescent microparticle immunoassay for quantitative determination of hepatitis C virus core antigen

2009 • 133 citations

Liver stiffness diminishes with antiviral response in chronic hepatitis C

2011 • 131 citations

Improvement of Hepatitis C Virus (HCV) Genotype Determination with the New Version of the INNO-LiPA HCV Assay

2007 • 125 citations

Evaluation of Versant Hepatitis C Virus Genotype Assay (LiPA) 2.0

2008 • 124 citations

Hepatitis C Virus (HCV) Genotype 1 Subtype Identification in New HCV Drug Development and Future Clinical Practice

2009 • 122 citations

GT-1a or GT-1b Subtype-Specific Resistance Profiles for Hepatitis C Virus Inhibitors Telaprevir and HCV-796

2009 • 122 citations

Non-invasive assessment of liver fibrosis: are we ready?

2010 • 121 citations

Simultaneous Detection of Hepatitis C Virus (HCV) Core Antigen and Anti-HCV Antibodies Improves the Early Detection of HCV Infection

2005 • 114 citations

Evaluation of a new, rapid test for detecting HCV infection, suitable for use with blood or oral fluid

2010 • 112 citations

Multi-center evaluation of the Abbott RealTime HCV Assay for monitoring patients undergoing antiviral therapy for chronic hepatitis C

2011 • 100 citations

New Automated Hepatitis C Virus (HCV) Core Antigen Assay as an Alternative to Real-Time PCR for HCV RNA Quantification

2010 • 98 citations

Evaluation of Three Rapid Screening Assays for Detection of Antibodies to Hepatitis C Virus

2011 • 94 citations

Anti-fibrotic therapy: Lost in translation?

2012 • 93 citations

Performance and clinical utility of a novel fully automated quantitative HCV-core antigen assay

2009 • 92 citations

Analytical evaluation of HCV core antigen and interest for HCV screening in haemodialysis patients

2010 • 89 citations

A practical guide for the use of boceprevir and telaprevir for the treatment of hepatitis C

2012 • 83 citations

Virological tools to diagnose and monitor hepatitis C virus infection

2010 • 77 citations

Performance of Premarket Rapid Hepatitis C Virus Antibody Assays in 4 National Human Immunodeficiency Virus Behavioral Surveillance System Sites

2011 • 76 citations

Clinical relevance of detectable but not quantifiable hepatitis C virus RNA during boceprevir or telaprevir treatment

2011 • 72 citations

Diagnostic accuracy, reproducibility and robustness of fibrosis blood tests in chronic hepatitis C: A meta-analysis with individual data

2008 • 71 citations

Second-Generation Cobas AmpliPrep/Cobas TaqMan HCV Quantitative Test for Viral Load Monitoring: a Novel Dual-Probe Assay Design

2012 • 68 citations

Current HIV epidemiology and revised recommendations for HIV testing in health-care settings

2007 • 61 citations

Laboratory Evaluation of a Fully Automated Chemiluminescence Immunoassay for Rapid Detection of HBsAg, Antibodies to HBsAg, and Antibodies to Hepatitis C Virus

2004 • 55 citations

Multicenter evaluation of a fully automated third-generation anti-HCV antibody screening test with excellent sensitivity and specificity

2010 • 52 citations

Accuracy of a commercially available assay for HCV genotyping and subtyping in the clinical practice

2013 • 44 citations

Performance Evaluation of the New Roche cobas AmpliPrep/cobas TaqMan HCV Test, Version 2.0, for Detection and Quantification of Hepatitis C Virus RNA

2012 • 43 citations

Sequencing Assays for Failed Genotyping with the Versant Hepatitis C Virus Genotype Assay (LiPA), Version 2.0

2013 • 42 citations

Clinical utility of the ARCHITECT HCV Ag assay for early treatment monitoring in patients with chronic hepatitis C genotype 1 infection

2012 • 40 citations

The Cobas AmpliPrep/Cobas TaqMan HCV Test, Version 2.0, Real-Time PCR Assay Accurately Quantifies Hepatitis C Virus Genotype 4 RNA

2013 • 39 citations

Performance characteristics of the ARCHITECT® Anti-HCV assay

2005 • 32 citations

A multicenter evaluation of the Abbott RealTime HCV Genotype II assay

2010 • 31 citations

Strong Correlation between Liver and Serum Levels of Hepatitis C Virus Core Antigen and RNA in Chronically Infected Patients

2011 • 30 citations

An evaluation of the performance of OraQuick® ADVANCE Rapid HIV-1/2 Test in a high-risk population attending genitourinary medicine clinics in East London, UK

2008 • 26 citations

Hepatitis C virus Core Antigen as a predictor of non-response in genotype 1 chronic hepatitis C patients treated with peginterferon α-2b plus ribavirin

2003 • 24 citations

Clinical performances of two real-time PCR assays and bDNA/TMA to early monitor treatment outcome in patients with chronic hepatitis C

2009 • 22 citations

A Boceprevir Failure in a Patient Infected with HCV Genotype 1G: Importance and Limitations of Virus Genotyping Prior to HCV Protease-Inhibitor-Based Therapy

2013 • 20 citations

Clinical usefulness of total hepatitis C virus core antigen quantification to monitor the response to treatment with peginterferon alpha‐2a plus ribavirin*

2005 • 18 citations

Performance of the Abbott RealTime HCV Genotype II RUO Assay

2012 • 18 citations

Performance evaluation of the Artus hepatitis C virus QS-RGQ assay

2011 • 15 citations

Performance of the Novel Qiagen artus QS-RGQ Viral Load Assays Compared to That of the Abbott RealTi m e System with Genetically Diversified HIV and Hepatitis C Virus Plasma Specimens

2012 • 11 citations

Closing in on the Target: Sustained Virologic Response in Hepatitis C Virus Genotype 1 Infection Response-Guided Therapy

2013 • 9 citations

Treatment of chronic hepatitis C genotype 1 with triple therapy comprising telaprevir or boceprevir

2012 • 9 citations

Evaluation of in-house and commercial genotyping assays for molecular typing of hepatitis C virus in Hong Kong

2010 • 5 citations

[Assessment of hepatic fibrosis].

1992 • 4 citations

Update of the Belgian Association for the Study of the Liver guidelines for the treatment of chronic hepatitis C genotype 1 with protease inhibitors.

2012 • 3 citations