SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

1998 • 3,700 citations

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

1994 • 3,477 citations

The coregulator exchange in transcriptional functions of nuclear receptors

2000 • 2,219 citations

Brain Lesions, Obesity, and Other Disturbances in Mice Treated with Monosodium Glutamate

1969 • 1,802 citations

Nuclear Hormone Receptors and Gene Expression

2001 • 1,538 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.

1996 • 1,169 citations

The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes

2000 • 1,125 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

1993 • 1,057 citations

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

2001 • 718 citations

Partial Hormone Resistance in Mice with Disruption of the Steroid Receptor Coactivator-1 (SRC-1) Gene

1998 • 685 citations

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1998 • 609 citations

Activation of PPARγ Coactivator-1 Through Transcription Factor Docking

1999 • 584 citations

Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice

2000 • 577 citations

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

2000 • 531 citations

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

1998 • 516 citations

Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes.

1995 • 459 citations

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

2002 • 446 citations

36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO

1991 • 432 citations

Regulation of Peroxisome Proliferator-Activated Receptor γ Expression by Adipocyte Differentiation and Determination Factor 1/Sterol Regulatory Element Binding Protein 1: Implications for Adipocyte Differentiation and Metabolism

1999 • 424 citations

Thermogenic Responses in Brown Fat Cells Are Fully UCP1-dependent

2000 • 323 citations

Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis

2002 • 314 citations

A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation

1999 • 309 citations

A Unique PPARγ Ligand with Potent Insulin-Sensitizing yet Weak Adipogenic Activity

2001 • 270 citations

The Function of TIF2/GRIP1 in Mouse Reproduction Is Distinct from Those of SRC-1 and p/CIP

2002 • 253 citations

Peroxisome proliferator and retinoid signalingpathways co-regulate preadipocyte phenotype and survival.

1994 • 227 citations

p300 Interacts with the N- and C-terminal Part of PPARγ2 in a Ligand-independent and -dependent Manner, Respectively

1999 • 224 citations

Peroxisome Targeting Signal of Rat Liver Acyl-Coenzyme A Oxidase Resides at the Carboxy Terminus

1989 • 197 citations

5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells

1997 • 196 citations

Regulation of somatic growth by the p160 coactivator p/CIP

2000 • 193 citations

Ligand type-specific Interactions of Peroxisome Proliferator-activated Receptor γ with Transcriptional Coactivators

2000 • 189 citations

A Potent Antidiabetic Thiazolidinedione with Unique Peroxisome Proliferator-activated Receptor γ-activating Properties

1998 • 188 citations

Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ER ^T2 ) in adipocytes

2000 • 171 citations

Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice

2002 • 153 citations

Regulation of Lipoprotein Metabolism by Thiazolidinediones Occurs through a Distinct but Complementary Mechanism Relative to Fibrates

1997 • 146 citations

Overexpression and Ribozyme-mediated Targeting of Transcriptional Coactivators CREB-binding Protein and p300 Revealed Their Indispensable Roles in Adipocyte Differentiation through the Regulation of Peroxisome Proliferator-activated Receptor γ

2002 • 144 citations

Activation of Peroxisome Proliferator-activated Receptor γ Bypasses the Function of the Retinoblastoma Protein in Adipocyte Differentiation

1999 • 143 citations

Analysis of a Tissue-Specific Enhancer: ARF6 Regulates Adipogenic Gene Expression

1992 • 137 citations

Peroxisome targeting signal of rat liver acyl-coenzyme A oxidase resides at the carboxy terminus.

1989 • 117 citations

Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes

2000 • 106 citations

Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2

1997 • 102 citations

The effects of topiramate and sex hormones on energy balance of male and female rats

2002 • 77 citations

Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor α-regulated gene expression

1999 • 75 citations

Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.

1992 • 75 citations

Leptin and Corticosterone Have Opposite Effects on Food Intake and the Expression of UCP1 mRNA in Brown Adipose Tissue oflep^ob/lep^obMice

1998 • 58 citations

Thyroid Function in Mice with Compound Heterozygous and Homozygous Disruptions of SRC-1 and TIF-2 Coactivators: Evidence for Haploinsufficiency

2002 • 42 citations

Partial purification by guanosine‐5′‐diphosphate—agarose affinity chromatography of the 32 000 molecular weight polypeptide from mitochondria of brown adipose tissue

1979 • 32 citations

Major thermogenic defect associated with insulin resistance in brown adipose tissue of obese diabetic SHR/N-cp rats

1991 • 29 citations

Hormones and the ob gene product (leptin) in the control of energy balance

1996 • 29 citations

Triglyceride-lowering agents: fibrates and nicotinic acid

1993 • 25 citations

Three Amino Acids Specify Coactivator Choice By Retinoid X Receptors

2000 • 21 citations

Hormonal and metabolic response to physical exercise, fasting and cold exposure in the rat

1988 • 14 citations

Tissue specificity of SNS response to exercise in mice exposed to low temperatures

1992 • 9 citations