Identification of the methyl phosphotriester of thymidylyl (3′-5′)thymidine as a product from reaction of DNA with the carcinogen N-methyl-N-nitrosourea

Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels

1972 • 185 citations

Studies on Polynucleotides. VIII.¹ Experiments on the Polymerization of Mononucleotides. Improved Preparation and Separation of Linear Thymidine Polynucleotides. Synthesis of Corresponding Members Terminated in Deoxycytidine Residues²

1961 • 184 citations

Specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo

1975 • 159 citations

Conformation and interaction of dinucleoside mono- and diphosphates. V. Syntheses and properties of adenine and thymine nucleoside alkyl phosphotriesters, the neutral analogs of dinucleoside monophosphates

1971 • 141 citations

Alkylation of Phosphates and Stability of Phosphate Triesters in DNA

1972 • 136 citations

Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O4-methyl-thymidine

1973 • 101 citations

Alkyl phosphotriesters of dinucleotides and oligonucleotides. 4. Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid

1974 • 84 citations

The alkylation of 2′-deoxyguanosine and of thymidine with diazoalkanes. Some observations on O-alkylation

1973 • 73 citations

Proton Magnetic Resonance Studies of 2′-Deoxythymidine, its 3′- and 5′-Monophosphates and 2′-Deoxythymidylyl-(3′, 5′)-2′ -deoxythymidine in Aqueous Solution

1974 • 73 citations

Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea—Evidence for transfer of the intact methyl group

1973 • 72 citations

Reaction of N-methyl-N-nitrosourea (MNUA) with 32P-labelled DNA: evidence for formation of phosphotriesters

1973 • 66 citations

Phosphotriesters in rat liver deoxyribonucleic acid after the administration of the carcinogen NN-dimethylnitrosamine in vivo

1975 • 42 citations

Studies on Polynucleotides. VII.¹ Approaches to the Marking of End Groups in Polynucleotide Chains: The Methylation of Phosphomonoester Groups²

1959 • 23 citations