CD44 phosphorylation regulates melanoma cell and fibroblast migration on, but not attachment to, a hyaluronan substratum

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

1996 • 1,106 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells.

1991 • 587 citations

Adhesion in cell migration

1995 • 520 citations

Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression

1994 • 436 citations

Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells.

1988 • 382 citations

Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.

1994 • 346 citations

CD44H regulates tumor cell migration on hyaluronate-coated substrate.

1992 • 334 citations

Distinct effects of two CD44 isoforms on tumor growth in vivo.

1991 • 315 citations

Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody.

1992 • 261 citations

Glycosylation of CD44 negatively regulates its recognition of hyaluronan.

1995 • 255 citations

Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.

1995 • 253 citations

Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function.

1994 • 249 citations

Hyaluronan on the surface of tumor cells is correlated with metastatic behavior.

1995 • 215 citations

Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation.

1995 • 196 citations

Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44.

1991 • 187 citations

Antibody‐induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody

1993 • 120 citations

Role of CD44 cytoplasmic domain in hyaluronan binding

1995 • 119 citations

Redistribution of a major cell surface glycoprotein during cell movement.

1984 • 115 citations

Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis.

1991 • 107 citations

The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts.

1993 • 104 citations

Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts

1995 • 102 citations

Lateral diffusion of an 80,000-dalton glycoprotein in the plasma membrane of murine fibroblasts: relationships to cell structure and function.

1984 • 100 citations

Identification and characterization of the human Pgp-1 glycoprotein

1986 • 97 citations

Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain.

1995 • 90 citations

CD44 exhibits a cell type dependent interaction with Triton X-100 insoluble, lipid rich, plasma membrane domains

1995 • 88 citations

How do cells move along surfaces?

1993 • 87 citations

Phosphorylation of CD44 in vivo requires both Ser323 and Ser325, but does not regulate membrane localization or cytoskeletal interaction in epithelial cells.

1992 • 80 citations

Hyaluronan binding by CD44 is regulated by a phosphorylation‐independent mechanism

1995 • 43 citations