Arrestin-independent Internalization of the m1, m3, and m4 Subtypes of Muscarinic Cholinergic Receptors

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.

1994 • 1,206 citations

β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function

1990 • 1,162 citations

THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN–COUPLED RECEPTOR REGULATION

1998 • 1,074 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

Primary Structure and Biochemical Properties of an M ₂ Muscarinic Receptor

1987 • 510 citations

Regulatory mechanisms that modulate signalling by G-protein-coupled receptors

1997 • 502 citations

Activation of the cloned muscarinic potassium channel by G protein βγ subunits

1994 • 472 citations

Dynamin and β-Arrestin Reveal Distinct Mechanisms for G Protein-coupled Receptor Internalization

1996 • 450 citations

A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation

1997 • 420 citations

The Role of Sequestration in G Protein-coupled Receptor Resensitization

1997 • 356 citations

Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence

1986 • 344 citations

Internalization and recycling of activated thrombin receptors

1993 • 271 citations

β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization

1993 • 201 citations

Modulation of the Arrestin-Clathrin Interaction in Cells

1997 • 193 citations

Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes.

1990 • 192 citations

Panning transfected cells for electrophysiological studies.

1993 • 189 citations

The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.

1995 • 176 citations

Internalization of the m2 Muscarinic Acetylcholine Receptor

1997 • 170 citations

The function of dynamin in endocytosis

1995 • 159 citations

Visualization of Agonist-induced Sequestration and Down-regulation of a Green Fluorescent Protein-tagged β2-Adrenergic Receptor

1998 • 158 citations

Polypeptide variants of beta-arrestin and arrestin3

1993 • 156 citations

Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor Are Directed by Independent Mechanisms

1995 • 155 citations

Hm1 muscarinic cholinergic receptor internalization requires a domain in the third cytoplasmic loop.

1992 • 129 citations

Two Homologous Phosphorylation Domains Differentially Contribute to Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor

1997 • 116 citations

[24] Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells

1995 • 109 citations

Serine- and threonine-rich domain regulates internalization of muscarinic cholinergic receptors.

1993 • 109 citations

Synergistic Regulation of m2 Muscarinic Acetylcholine Receptor Desensitization and Sequestration by G Protein-coupled Receptor Kinase-2 and β-Arrestin-1

1997 • 77 citations

Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases.

1995 • 68 citations

Role of Dynamin in Clathrin-eoated Vesicle Formation

1995 • 47 citations

G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration

1996 • 44 citations

Immunolocalization of X‐arrestin in human cone photoreceptors

1996 • 43 citations

Receptor internalization delays m4 muscarinic acetylcholine receptor resensitization at the plasma membrane.

1996 • 38 citations

Chapter 15 The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors

1996 • 17 citations