Kinesin light chain-independent function of theKinesin heavy chainin cytoplasmic streaming and posterior localisation in theDrosophilaoocyte

The Genome Sequence of Drosophila melanogaster

2000 • 5,882 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

oskar organizes the germ plasm and directs localization of the posterior determinant nanos

1991 • 804 citations

The Autosomal FLP-DFS Technique for Generating Germline Mosaics in Drosophila melanogaster

1996 • 652 citations

Induction of germ cell formation by oskar

1992 • 643 citations

staufen, a gene required to localize maternal RNAs in the Drosophila egg

1991 • 612 citations

A novel brain ATPase with properties expected for the fast axonal transport motor

1985 • 604 citations

Cargo of Kinesin Identified as Jip Scaffolding Proteins and Associated Signaling Molecules

2001 • 593 citations

Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP

2001 • 581 citations

oskar mRNA is localized to the posterior pole of the Drosophila oocyte

1991 • 574 citations

Microtubule-Based Transport Systems in Neurons: The Roles of Kinesins and Dyneins

2000 • 544 citations

Axonal Transport of Amyloid Precursor Protein Is Mediated by Direct Binding to the Kinesin Light Chain Subunit of Kinesin-I

2000 • 544 citations

A conserved double-stranded RNA-binding domain.

1992 • 540 citations

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

2002 • 517 citations

Polarization of both major body axes in Drosophila by gurken-torpedo signalling

1995 • 485 citations

cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila

1995 • 480 citations

Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner

1994 • 435 citations

Disruption of Axonal Transport and Neuronal Viability by Amyloid Precursor Protein Mutations in Drosophila

2001 • 424 citations

Reorganization of the cytoskeleton during Drosophila oogenesis: implications for axis specification and intercellular transport

1992 • 399 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Developmental Regulation of Vesicle Transport in Drosophila Embryos: Forces and Kinetics

1998 • 389 citations

Kinesin Mutations Cause Motor Neuron Disease Phenotypes by Disrupting Fast Axonal Transport in Drosophila

1996 • 375 citations

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila

1991 • 372 citations

A Function for Kinesin I in the Posterior Transport of oskar mRNA and Staufen Protein

2000 • 369 citations

Cytoplasmic Dynein, the Dynactin Complex, and Kinesin Are Interdependent and Essential for Fast Axonal Transport

1999 • 365 citations

RNA recognition by a Staufen double-stranded RNA-binding domain

2000 • 360 citations

Kinesin-Dependent Axonal Transport Is Mediated by the Sunday Driver (SYD) Protein

2000 • 321 citations

Kinesin’s tail domain is an inhibitory regulator of the motor domain

1999 • 312 citations

Autosomal P[ovo D1 ] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras

1993 • 302 citations

Interactions and regulation of molecular motors in Xenopus melanophores

2002 • 297 citations

Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte

1994 • 293 citations

The Drosophila Homolog of C. elegans PAR-1 Organizes the Oocyte Cytoskeleton and Directs oskar mRNA Localization to the Posterior Pole

2000 • 291 citations

Localization of Xenopus Vg1 mRNA by Vera Protein and the Endoplasmic Reticulum

1997 • 287 citations

Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain

1999 • 281 citations

Axis formation during Drosophila oogenesis

2001 • 274 citations

The Mammalian Staufen Protein Localizes to the Somatodendritic Domain of Cultured Hippocampal Neurons: Implications for Its Involvement in mRNA Transport

1999 • 272 citations

Light Chain– dependent Regulation of Kinesin's Interaction with Microtubules

1998 • 252 citations

The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport

1997 • 251 citations

The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila

1997 • 246 citations

Miranda mediates asymmetric protein and RNA localization in the developing nervous system

1998 • 246 citations

Mammalian Staufen Is a Double-Stranded-RNA- and Tubulin-Binding Protein Which Localizes to the Rough Endoplasmic Reticulum

1999 • 244 citations

A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm.

1990 • 242 citations

Reciprocal localization of Nod and kinesin fusion proteins indicates microtubule polarity in the Drosophila oocyte, epithelium, neuron and muscle

1997 • 221 citations

Kinectin, a major kinesin-binding protein on ER.

1992 • 215 citations

Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport

2001 • 213 citations

Requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization

1995 • 211 citations

Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis

1991 • 197 citations

In Vivo Analysis of Drosophila bicoid mRNA Localization Reveals a Novel Microtubule-Dependent Axis Specification Pathway

2001 • 194 citations

The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila

1997 • 194 citations

The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis

1999 • 188 citations

Kinesin Light Chains Are Essential for Axonal Transport in Drosophila

1998 • 173 citations

A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation

2000 • 173 citations

A Human Sequence Homologue of Staufen Is an RNA-Binding Protein That Is Associated with Polysomes and Localizes to the Rough Endoplasmic Reticulum

1999 • 169 citations

The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis

2001 • 168 citations

Rab11 polarization of theDrosophilaoocyte: a novel link between membrane trafficking, microtubule organization, andoskarmRNA localization and translation

2002 • 168 citations

Cytoplasmic flows localize injected oskar RNA in Drosophila oocytes

1997 • 163 citations

Kinectin, an Essential Anchor for Kinesin-Driven Vesicle Motility

1995 • 158 citations

Drosophila cytoplasmic dynein, a microtubule motor that is asymmetrically localized in the oocyte.

1994 • 157 citations

Premature Microtubule-Dependent Cytoplasmic Streaming in cappuccino and spire Mutant Oocytes

1994 • 153 citations

Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior

2002 • 152 citations

The role of microfilaments in cytoplasmic streaming in Drosophila follicles

1986 • 151 citations

Cargo binding and regulatory sites in the tail of fungal conventional kinesin

2000 • 148 citations

Immunochemical analysis of kinesin light chain function.

1997 • 146 citations

The mago nashi locus encodes an essential product required for germ plasm assembly in Drosophila

1994 • 141 citations

Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole

2001 • 141 citations

Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein.

1993 • 140 citations

Principles of cargo attachment to cytoplasmic motor proteins

2002 • 136 citations

In vivo analyses of cytoplasmic transport and cytoskeletal organization during Drosophila oogenesis: characterization of a multi-step anterior localization pathway

1998 • 133 citations

Flying through theDrosophilaCytoskeletal Genome

2000 • 130 citations

Connecting vesicle transport to the cytoskeleton

2000 • 128 citations

RNA localization along the anteroposterior axis of the Drosophila oocyte requires PKA-mediated signal transduction to direct normal microtubule organization.

1994 • 124 citations

Mutations in a newly identified Drosophila melanogaster gene, mago nashi, disrupt germ cell formation and result in the formation of mirror-image symmetrical double abdomen embryos

1991 • 115 citations

The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding.

1994 • 110 citations

Time-lapse film analysis of cytoplasmic streaming during late oogenesis of Drosophila

1982 • 109 citations

mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila

1997 • 101 citations

Centrosome migration into the Drosophila oocyte is independent of BicD and egl, and of the organisation of the microtubule cytoskeleton

2001 • 101 citations

The Neurospora organelle motor: a distant relative of conventional kinesin with unconventional properties.

1995 • 101 citations

Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants

1999 • 101 citations

The Drosophila kinesin light chain. Primary structure and interaction with kinesin heavy chain

1993 • 100 citations

Isolation of a 45-kDa Fragment from the Kinesin Heavy Chain with Enhanced ATPase and Microtubule-binding Activities

1989 • 96 citations

An Interaction Type of Genetic Screen Reveals a Role of the Rab11 Gene in oskar mRNA Localization in the Developing Drosophila melanogaster Oocyte

2001 • 82 citations

Lack of Drosophila cytoskeletal tropomyosin affects head morphogenesis and the accumulation of oskar mRNA required for germ cell formation.

1996 • 80 citations

Tetratrico peptide repeats are present in the kinesin light chain

1996 • 77 citations

Characterization of α2β2 and α2 forms of kinesin

1991 • 77 citations

Reversing Neurodegeneration:A Promise Unfolds

2000 • 76 citations

The role of microtubules in the differentiation of ovarian follicles during vitellogenesis inDrosophila

1986 • 67 citations

The rate-limiting step in microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains occurs while bound to the microtubule.

1994 • 66 citations

Kinectin-Kinesin Binding Domains and Their Effects on Organelle Motility

2000 • 58 citations

Cytoskeleton-dependent transport of cytoplasmic particles in previtellogenic to mid-vitellogenic ovarian follicles of Drosophila: time-lapse analysis using video-enhanced contrast microscopy

1994 • 52 citations

Intact Lysosome Transport and Phagosome Function Despite Kinectin Deficiency

2001 • 23 citations