Effects of Methionine-Induced Hyperhomocysteinemia on Endothelium-Dependent Vasodilation and Oxidative Status in Healthy Adults

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis

1992 • 4,765 citations

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

1995 • 3,645 citations

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

1991 • 2,191 citations

Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo

1995 • 1,632 citations

Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

1994 • 1,326 citations

Antioxidant defenses and lipid peroxidation in human blood plasma.

1988 • 1,253 citations

Total homocysteine in plasma or serum: methods and clinical applications

1993 • 996 citations

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation.

1985 • 886 citations

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.

1993 • 865 citations

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

1986 • 826 citations

Socioeconomic determinants of health: The contribution of nutrition to inequalities in health

1997 • 716 citations

Hyperhomocyst(e)inemia Is Associated With Impaired Endothelium-Dependent Vasodilation in Humans

1997 • 698 citations

Generation of Superoxide Free Radical during the Autoxidation of Thiols

1974 • 558 citations

Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma

1992 • 503 citations

Hyperhomocyst(e)inemia Is a Risk Factor for Arterial Endothelial Dysfunction in Humans

1997 • 495 citations

Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia

1993 • 475 citations

Demonstration of Rapid Onset Vascular Endothelial Dysfunction After Hyperhomocysteinemia

1999 • 440 citations

Prospective Study of Hyperhomocysteinemia as an Adverse Cardiovascular Risk Factor in End-Stage Renal Disease

1998 • 412 citations

Rapid, fully automated measurement of plasma homocyst(e)ine with the Abbott IMx analyzer

1995 • 380 citations

Hyperhomocysteinemia After an Oral Methionine Load Acutely Impairs Endothelial Function in Healthy Adults

1998 • 342 citations

Levels of Soluble Cell Adhesion Molecules in Patients With Dyslipidemia

1996 • 308 citations

Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation

1994 • 283 citations

Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not in their heterozygous parents

1993 • 259 citations

Nitric Oxide Protects Against Leukocyte-Endothelium Interactions in the Early Stages of Hypercholesterolemia

1995 • 243 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of thiol compounds

1982 • 214 citations

Fully automated fluorescence assay for determining total homocysteine in plasma.

1989 • 208 citations

Increased Levels of Soluble P-Selectin in Hypercholesterolemic Patients

1998 • 169 citations

Endothelial dysfunction by acute hyperhomocyst(e)inaemia: restoration by folic acid

1999 • 148 citations

Vitamin requirements of elderly people: an update

1993 • 145 citations

Alternatively spliced isoform of P-selectin is present in vivo as a soluble molecule.

1994 • 118 citations

Stimulation of endothelial nitric oxide production by homocyst(e)ine

1997 • 112 citations

Lipid peroxidation and susceptibility of low‐density lipoprotein to in vitro oxidation in hyperhomocysteinaemia

1995 • 109 citations

Structural and Biosynthetic Studies of the Granule Membrane Protein, GMP-140, from Human Platelets and Endothelial Cells

1989 • 107 citations

Regulation of P-selectin expression in human endothelial cells by nitric oxide

1997 • 99 citations

Presence of Phosphatidylcholine Hydroperoxide in Human Plasma

1988 • 93 citations

Circulating lipid hydroperoxide levels in human hyperhomocysteinemia. Relevance to development of arteriosclerosis.

1993 • 81 citations

Lipid peroxidation and homocysteine induced toxicity

1994 • 69 citations

Lipid peroxidation induced in vivo by hyperhomocysteinaemia in pigs

1997 • 53 citations

Chinese Adults Are Less Susceptible Than Whites to Age-Related Endothelial Dysfunction

1997 • 53 citations

Extensive laboratory assessment of nutritional status in fit, health-conscious, elderly people living in the Paris area. Research Group on Aging.

1994 • 41 citations

Peroxidative stress and in vitro ageing of endothelial cells increases the monocyte-endothelial cell adherence in a human in vitro system

1989 • 36 citations