Concerted Action of the High Affinity Calcium Binding Sites in Skeletal Muscle Troponin C

[18] Purification of muscle actin

1982 • 1,186 citations

Structure And Evolution Of Calcium-Modulated Protein

1980 • 942 citations

The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

1975 • 917 citations

A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase

1981 • 891 citations

CRYSTAL STRUCTURES OF THE HELIX-LOOP-HELIX CALCIUM-BINDING PROTEINS

1989 • 855 citations

Structural Aspects of Troponin-Tropomyosin Regulation of Skeletal Muscle Contraction

1987 • 529 citations

The time-course of Ca2+ exchange with calmodulin, troponin, parvalbumin, and myosin in response to transient increases in Ca2+

1981 • 415 citations

Troponin and Its Components*

1971 • 332 citations

Purification and Properties of the Components from Troponin

1973 • 329 citations

Variations in cross-bridge attachment rate and tension with phosphorylation of myosin in mammalian skinned skeletal muscle fibers. Implications for twitch potentiation in intact muscle.

1989 • 286 citations

[21] Preparation and identification of α- and β-tropomyosins

1982 • 259 citations

Structural and regulatory functions of the NH2- and COOH-terminal regions of skeletal muscle troponin I.

1994 • 213 citations

Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T

1978 • 209 citations

A fluorescence stopped flow analysis of Ca2+ exchange with troponin C.

1979 • 185 citations

Ca2+ regulation of mechanical properties of striated muscle. Mechanistic studies using extraction and replacement of regulatory proteins.

1992 • 176 citations

Calcium-binding properties of troponin C in detergent-skinned heart muscle fibers.

1987 • 153 citations

Chemically skinned mammalian skeletal muscle I. The structure of skinned rabbit psoas

1979 • 149 citations

A structural role for the Ca2+-Mg2+ sites on troponin C in the regulation of muscle contraction. Preparation and properties of troponin C depleted myofibrils.

1982 • 148 citations

Molecular mechanism of troponin-C function

1992 • 140 citations

Proteolytic fragments of troponin C. Interactions with the other troponin subunits and biological activity.

1981 • 137 citations

Ionic interactions with parvalbumins

1991 • 135 citations

The effects of partial extraction of TnC upon the tension-pCa relationship in rabbit skinned skeletal muscle fibers.

1985 • 132 citations

Isoforms of C-protein in adult chicken skeletal muscle: detection with monoclonal antibodies.

1982 • 115 citations

Co-operative interactions between troponin-tropomyosin units extend the length of the thin filament in skeletal muscle

1987 • 111 citations

The thin filament of vertebrate skeletal muscle co-operatively activates as a unit

1984 • 111 citations

Probing the calcium-induced conformational transition of troponin C with site-directed mutants

1990 • 99 citations

Calmodulin and troponin C structures studied by Fourier transform infrared spectroscopy: effects of calcium and magnesium binding

1989 • 93 citations

Kinetic studies of calcium binding to regulatory complexes from skeletal muscle.

1985 • 87 citations

Calmodulin-free skeletal-muscle troponin C prepared in the absence of urea

1981 • 74 citations

Isolation, expression, and mutation of a rabbit skeletal muscle cDNA clone for troponin I. The role of the NH2 terminus of fast skeletal muscle troponin I in its biological activity.

1992 • 73 citations

Evidence that both Ca(2+)-specific sites of skeletal muscle TnC are required for full activity.

1990 • 59 citations

Binary interactions of troponin subunits.

1984 • 59 citations

Mutation of the high affinity calcium binding sites in cardiac troponin C.

1992 • 55 citations

Properties of isolated recombinant N and C domains of chicken troponin C

1994 • 54 citations

Determination of and corrections to sequences of turkey and chicken troponins-C. Effects of Thr-130 to Ile mutation on Ca2+ affinity

1991 • 52 citations

Study of the structure of troponin-C by measuring the relative reactivities of lysines with acetic anhydride

1981 • 49 citations

Comparison of the calcium- and magnesium-induced structural changes of troponin-C

1978 • 48 citations

Effects of EDTA treatment upon the protein subunit composition and mechanical properties of mammalian single skeletal muscle fibers

1983 • 46 citations

The effects of N helix deletion and mutant F29W on the Ca2+ binding and functional properties of chicken skeletal muscle troponin.

1994 • 44 citations

Interaction of troponin C and troponin C fragments with troponin I and the troponin I inhibitory peptide

1992 • 43 citations

Direct identification of the high and low affinity calcium binding sites of troponin-C

1978 • 40 citations

Energetics of the binding of calcium and troponin I to troponin C from rabbit skeletal muscle

1985 • 40 citations

Troponin‐C mutants with increased calcium affinity

1993 • 39 citations

Symmetrical rearrangement of the cation-binding sites of parvalbumin upon calcium/magnesium exchange. A study by proton 2D NMR

1993 • 39 citations

Function of the N-terminal calcium-binding sites in cardiac/slow troponin C assessed in fast skeletal muscle fibers

1991 • 39 citations

Ca2+, Mg2+, and Troponin I Inhibitory Peptide Binding to a Phe-154 to Trp Mutant of Chicken Skeletal Muscle Troponin C

1994 • 35 citations

A comparative spectroscopic study of tryptophan probes engineered into high- and low-affinity domains of recombinant chicken troponin C

1992 • 34 citations

Functional delineation of the Ca(2+)-deficient EF-hand in cardiac muscle, with genetically engineered cardiac-skeletal chimeric troponin C.

1992 • 34 citations

The effects of deletion of the amino-terminal helix on troponin C function and stability

1994 • 32 citations

Interactions of troponin subunits: free energy of binary and ternary complexes

1987 • 28 citations

Critical minimum length of the central helix in troponin C for the Ca2+ switch in muscular contraction.

1993 • 26 citations

Ca(2+)-dependence of structural changes in troponin-C in demembranated fibers of rabbit psoas muscle

1992 • 26 citations

Fluorescence lifetime and acrylamide quenching studies of the interactions between troponin subunits

1984 • 24 citations

Differential recovery of Ca2+ binding activity in mutated EF-hands of cardiac troponin C.

1993 • 22 citations

Calmodulin supports the force-generating function in desensitized muscle fibers.

1988 • 21 citations

Direct evidence for the calcium-induced change in the quaternary structure of troponin in situ. Millisecond crosslinking of troponin components by a photosensitive heterobifunctional reagent

1980 • 21 citations

Calcium plays distinctive structural roles in the N- and C-terminal domains of cardiac troponin C.

1993 • 20 citations

Calmodulin and troponin C: affinity chromatographic study of divalent cation requirements for troponin I inhibitory peptide (residues 104–115), mastoparan, and fluphenazine binding

1987 • 18 citations

1H-NMR Study of Ca2+- and Mg2+-Dependent Interaction between Troponin C and Troponin I Inhibitory Peptide (96–116)1

1992 • 13 citations