A structural role for the Ca2+-Mg2+ sites on troponin C in the regulation of muscle contraction. Preparation and properties of troponin C depleted myofibrils.

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

Calcium and muscle contraction

1968 • 1,745 citations

The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

1975 • 917 citations

Calcium-binding proteins and calcium function

1977 • 742 citations

Reconstitution of Troponin Activity from Three Protein Components

1971 • 594 citations

Structural Changes in the Actin- and Myosin-eontaining Filaments during Contraction

1973 • 544 citations

Troponin-Tropomyosin Complex

1974 • 488 citations

Physicochemical properties of rat testis Ca2+-dependent regulator protein of cyclic nucleotide phosphodiesterase. Relationship of Ca2+-binding, conformational changes, and phosphodiesterase activity

1977 • 459 citations

The time-course of Ca2+ exchange with calmodulin, troponin, parvalbumin, and myosin in response to transient increases in Ca2+

1981 • 415 citations

[22] Preparation of troponin and its subnits

1982 • 345 citations

Troponin, tripomyosin, and actin interactions in the Ca²⁺ion regulation of muscle contraction

1974 • 299 citations

The content of troponin, tropomyosin, actin, and myosin in rabbit skeletal muscle myofibrils

1974 • 219 citations

The interaction of the calcium-binding protein (troponin C) with bivalent cations and the inhibitory protein (troponin I)

1974 • 218 citations

The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

1980 • 218 citations

Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T

1978 • 209 citations

The relaxing protein system of striated muscle. Resolution of the troponin complex into inhibitory and calcium ion-sensitizing factors and their relationship to tropomyosin

1969 • 201 citations

A fluorescence stopped flow analysis of Ca2+ exchange with troponin C.

1979 • 185 citations

The Croonian Lecture, 1979: Regulation of muscle contraction

1980 • 170 citations

Calcium sensitive binding of troponin to actin-tropomyosin: A two-site model for troponin action

1973 • 154 citations

Fractionation of troponin into two distinct proteins

1968 • 138 citations

Calcium and Cell Function

1982 • 134 citations

Dansylaziridine-labeled troponin C. A fluorescent probe of Ca2+ binding to the Ca2+-specific regulatory sites.

1978 • 123 citations

Atomic Absorption Spectroscopy

1966 • 121 citations

Atomic Absorption Spectroscopy

1960 • 119 citations

Effect of Ca2+ binding on troponin C. Changes in spin label mobility, extrinsic fluorescence, and sulfhydryl reactivity.

1976 • 101 citations

Regulatory Proteins of Muscle with Special Reference to Troponin

1973 • 89 citations

Characterization of a region of the primary sequence of troponin C involved in calcium ion-dependent interaction with troponin I

1978 • 82 citations

Detection of two classes of Ca2+ binding sites in troponin C with circular dichroism and tyrosine fluorescence.

1978 • 80 citations

Thermodynamics of Ca2+ binding to troponin-C.

1977 • 80 citations

Calmodulin-free skeletal-muscle troponin C prepared in the absence of urea

1981 • 74 citations

Molecular Basis of Motility

1976 • 72 citations

The adeonosine-triphosphatase activity of desensitized actomyosin

1967 • 71 citations

Muscle contraction. Its regulatory mechanisms

1982 • 71 citations

The effect of Mg++ on the conformation of the Ca++-binding component of troponin

1972 • 71 citations

Interaction of calmodulin with skeletal muscle myosin light chain kinase

1981 • 61 citations

Calcium-induced conformational changes in a cyanogen bromide fragment of troponin C that contains one of the binding sites.

1978 • 57 citations

Extent and localization of conformational changes in troponin C caused by calcium binding. Spectral studies in the presence and absence of 6 M urea.

1979 • 54 citations

The binding of calcium to glycerinated muscle fibers in rigor. The effect of filament overlap

1977 • 51 citations

The Ca2+ and Mg2+ dependence of Ca2+ uptake and respiratory function of porcine heart mitochondria. Probable physiological significance during the cardiac contraction-relaxation cycle.

1982 • 46 citations

Study of the structure of troponin-T by measuring the relative reactivities of lysines with acetic anhydride

1981 • 40 citations

Cell and Muscle Motility

1981 • 35 citations

Purification of Actin from Cardiac Muscle

1981 • 34 citations

Calmodulin as a model for troponin C

1980 • 21 citations

Direct evidence for the calcium-induced change in the quaternary structure of troponin in situ. Millisecond crosslinking of troponin components by a photosensitive heterobifunctional reagent

1980 • 21 citations