Gcn5p, a Transcription-related Histone Acetyltransferase, Acetylates Nucleosomes and Folded Nucleosomal Arrays in the Absence of Other Protein Subunits

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

1998 • 568 citations

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

1996 • 525 citations

Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

1998 • 490 citations

Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines

1997 • 480 citations

Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo

1998 • 444 citations

The Major Cytoplasmic Histone Acetyltransferase in Yeast: Links to Chromatin Replication and Histone Metabolism

1996 • 429 citations

Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase

1998 • 344 citations

Identification of a Gene Encoding a Yeast Histone H4 Acetyltransferase

1995 • 341 citations

Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase

1998 • 318 citations

Boundary analysis of sedimentation‐velocity experiments with monodisperse and paucidisperse solutes

1978 • 311 citations

Two-Dimensional Gel Analysis of Histones in Acid Extracts of Nuclei, Cells, and Tissues

1980 • 242 citations

Homogeneous reconstituted oligonucleosomes, evidence for salt-dependent folding in the absence of histone H1

1989 • 224 citations

Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function invivo

1997 • 208 citations

Role for ADA/GCN5 Products in Antagonizing Chromatin-Mediated Transcriptional Repression

1997 • 203 citations

Core Histone Tail Domains Mediate Oligonucleosome Folding and Nucleosomal DNA Organization through Distinct Molecular Mechanisms

1995 • 173 citations

Histone Acetyltransferase Activity Is Conserved between Yeast and Human GCN5 and Is Required for Complementation of Growth and Transcriptional Activation

1997 • 168 citations

Formation and stability of higher order chromatin structures. Contributions of the histone octamer.

1994 • 163 citations

Mammalian GCN5 and P/CAF Acetyltransferases Have Homologous Amino-Terminal Domains Important for Recognition of Nucleosomal Substrates

1998 • 162 citations

Core Histones Are Glutaminyl Substrates for Tissue Transglutaminase

1996 • 124 citations

Histone Acetylation Is Required to Maintain the Unfolded Nucleosome Structure Associated with Transcribing DNA

1998 • 110 citations

Cloning of Drosophila GCN5: Conserved features among metazoan GCN5 family members

1998 • 108 citations

HAT1 and HAT2 Proteins Are Components of a Yeast Nuclear Histone Acetyltransferase Enzyme Specific for Free Histone H4

1998 • 99 citations

Nuclear matrix, dynamic histone acetylation and transcriptionally active chromatin.

1997 • 95 citations

Influence of chromatin folding on transcription initiation and elongation by RNA polymerase III

1992 • 92 citations

A role for histones H2A/H2B in chromatin folding and transcriptional repression.

1994 • 84 citations

Rearrangement of the histone H2A C-terminal domain in the nucleosome.

1994 • 75 citations

Genetic evidence for the interaction of the yeast transcriptional co-activator proteins GCN5 and ADA2

1995 • 70 citations

Gcn5p is involved in the acetylation of histone H3 in nucleosomes

1997 • 62 citations

Binding of the RNA polymerase I transcription complex to its promoter can modify positioning of downstream nucleosomes assembled in vitro.

1993 • 44 citations

The role of histones and their modifications in the informative content of chromatin

1993 • 41 citations

The Gcn5·Ada Complex Potentiates the Histone Acetyltransferase Activity of Gcn5

1998 • 31 citations

Partial purification and properties of two histone acetyltransferases from the yeast, Saccharomyces cerevisiae

1985 • 27 citations