Nicotine-induced excitation of locus coeruleus neurons is blocked by elevated levels of endogenous kynurenic acid

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Nucleus locus ceruleus: new evidence of anatomical and physiological specificity

1983 • 1,877 citations

Neuropharmacology of quinolinic and kynurenic acids.

1993 • 920 citations

Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal.

1980 • 836 citations

The Role of Locus Coeruleus in the Regulation of Cognitive Performance

1999 • 707 citations

Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons

1977 • 490 citations

Noradrenergic neurons: Morphine inhibition of spontaneous activity

1974 • 433 citations

Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain

1988 • 342 citations

Presence of Kynurenic Acid in the Mammalian Brain

1988 • 273 citations

Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors

1990 • 256 citations

A potent excitatory input to the nucleus locus coeruleus from the ventrolateral medulla

1986 • 235 citations

Identification and quantification of kynurenic acid in human brain tissue

1988 • 217 citations

Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection

1990 • 126 citations

(R,S)-3,4-dichlorobenzoylalanine (FCE 28833A) causes a large and persistent increase in brain kynurenic acid levels in rats

1996 • 97 citations

Age-related changes in kynurenic acid production in rat brain

1992 • 94 citations

Potent inhibitory input to locus coeruleus from the nucleus prepositus hypoglossi

1989 • 86 citations

Blockade of Smoking Satisfaction Using the Peripheral Nicotinic Antagonist Trimethaphan

1999 • 81 citations

Role of primary sensory neurons in the central effects of nicotine

1988 • 37 citations

The rat nucleus paragigantocellularis as a relay station to mediate peripherally induced central effects of nicotine

1989 • 35 citations

Nicotine induced excitation of locus coeruleus neurons is mediated via release of excitatory amino acids

1989 • 33 citations

Nicotine-induced activation of locus coeruleus neurons —an analysis of peripheral versus central induction

1994 • 31 citations