Antagonists of the Platelet‐activating Factor Receptor Block Long‐term Potentiation in Hippocampal Slices

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

Perspectives in platelet-activating factor research.

1987 • 1,383 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

The role of calcium in neuromuscular facilitation

1968 • 1,331 citations

Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators).

1979 • 1,203 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

1987 • 934 citations

Platelet-activating factor.

1990 • 904 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Induction of Synaptic Potentiation in Hippocampus by Patterned Stimulation Involves Two Events

1986 • 603 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice

1984 • 531 citations

Contributions of Quisqualate and NMDA Receptors to the Induction and Expression of LTP

1988 • 512 citations

Brief bursts of high-frequency stimulation produce two types of structural change in rat hippocampus.

1980 • 474 citations

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid).

1981 • 440 citations

Identification of platelet activating factor isolated from rabbit basophils as acetyl glyceryl ether phosphorylcholine.

1980 • 408 citations

NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat

1990 • 360 citations

CV-3988 - A specific antagonist of platelet activating factor (PAF)

1983 • 341 citations

Enzymatic synthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, a hypotensive and platelet-aggregating lipid.

1980 • 321 citations

Role of N-methyl-D-aspartate receptors in the induction of synaptic potentiation by burst stimulation patterned after the hippocampal θ-rhythm

1988 • 243 citations

Neuroregulatory and Neuropathological Actions of the Ether-Phospholipid Platelet-Activating Factor

1988 • 243 citations

The relationship between extracellular calcium concentrations and the induction of hippocampal long-term potentiation

1979 • 234 citations

Specific receptor sites for 1-0-alkyl-2-0-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) on rabbit platelet and guinea pig smooth muscle membranes

1983 • 230 citations

Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex.

1990 • 213 citations

Changes in the postsynaptic density with long‐term potentiation in the dentate gyrus

1986 • 206 citations

Production and effects of platelet-activating factor in the rat brain

1988 • 205 citations

Effects of a platelet activating factor antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: Inhibition of ischemia-reperfusion induced cerebral injury

1987 • 159 citations

Semi-synthèse et structure proposée du facteur activant les plaquettes (P.A.F.): PAF-acether, un alkyl ether analogue de la lysophosphatidylcholine.

1979 • 149 citations

Dantrolene-Na (Dantrium) blocks induction of long-term potentiation in hippocampal slices

1989 • 144 citations

The effects of adenosine on the development of long-term potentiation

1990 • 137 citations

Evidence that matrix recognition contributes to stabilization but not induction of LTP

1991 • 135 citations

An inhibitor of integrin receptors blocks long-term potentiation

1990 • 128 citations

trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.

1985 • 120 citations

Inhibition of protein kinase C blocks two components of LTP persistence, leaving initial potentiation intact

1990 • 107 citations

Development of hippocampal long-term potentiation is reduced by recently introduced calpain inhibitors

1990 • 102 citations

Benzodiazepines block long-term potentiation in slices of hippocampus and piriform cortex

1992 • 102 citations

Stimulation of Platelet-activating Factor Synthesis by a Nonmetabolizable Bioactive Analog of Platelet-activating Factor and Influence of Arachidonic Acid Metabolites

1989 • 98 citations

Human serum acid-labile factor is an acylhydrolase that inactivates platelet-activating factor.

1983 • 98 citations

Calcium dependency of synaptic long-lasting potentiation in the hippocampal slice

1979 • 96 citations

Anoxia reveals a vulnerable period in the development of long-term potentiation

1990 • 94 citations

Onset Characteristics of Long‐Term Potentiation in the Guinea‐Pig Hippocampal CA1 Region in Vitro

1989 • 93 citations

Production of Platelet‐Activating Factor from Rat Cerebellar Granule Cells in Culture

1990 • 92 citations

Formation of 1-alkyl-2-acetyl-sn-glycerols via the de novo biosynthetic pathway for platelet-activating factor. Characterization of 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase in rat spleens.

1988 • 72 citations

The de novo biosynthesis of Platelet-Activating Factor in rat brain

1989 • 68 citations

Protein kinase C activity is not responsible for the expression of long-term potentiation in hippocampus.

1990 • 68 citations

1-0-alkyl-2-N-methylcarbamyl-glycerophosphocholine: A biologically potent, non-metabolizable analog of platelet-activating factor

1987 • 68 citations

Binding and internalization of platelet-activating factor 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine in washed rabbit platelets.

1987 • 67 citations

Inhibition of long-term potentiation by an antagonist of platelet-activating factor receptors

1990 • 67 citations

Chapter 16 Long-term potentiation in the hippocampal CA1 region: its induction and early temporal development

1990 • 64 citations

Conformation and activity of tetrahydrofuran lignans and analogs as specific platelet-activating-factor antagonists

1986 • 56 citations

The metabolism of lyso-platelet-activating factor (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) by a calcium-dependent lysophospholipase D in rabbit kidney medulla

1987 • 49 citations

Dual binding modes to the receptor for platelet activating factor (PAF) of anti-paf trans-2,5-diarylfurans

1988 • 38 citations

Identification of functional platelet-activating factor receptors in Raji lymphoblasts.

1989 • 35 citations

Two distinct pathways of platelet-activating factor-induced hydrolysis of phosphoinositides in primary cultures of rat Kupffer cells.

1990 • 33 citations

Some unique features of the metabolic conversion of platelet-activating factor (AGEPC) to alkyl acyl PC by washed rabbit platelets

1987 • 14 citations

Rate‐limiting step for transmission at excitatory synapses in hippocampus

1989 • 14 citations

Induction and Stabilization of Long-Term Potentiation

1991 • 13 citations