Genetic complementation after fusion of Tay-Sachs and Sandhoff cells

Tay-Sachs Disease: Generalized Absence of a Beta-D- N -Acetylhexosaminidase Component

1969 • 707 citations

Deficient hexosaminidase activity in an exceptional case of Tay-Sachs disease with additional storage of kidney globoside in visceral organs

1968 • 329 citations

Genetic Heterogeneity of Xeroderma Pigmentosum demonstrated by Somatic Cell Hybridization

1972 • 319 citations

Lysosomal hydrolases: Conversion of acidic to basic forms by neuraminidase

1971 • 148 citations

Poliovirus Replication and Cytopathogenicity in Monolayer Hamster Cell Cultures Fused with Beta Propiolactone-Inactivated Sendai Virus

1968 • 116 citations

Electrophoretic study of hexosaminidases. Hexosaminidase C

1973 • 94 citations

Interallelic Complementation in Hybrid Cells Derived from Human Diploid Strains Deficient in Galactose-1-Phosphate Uridyl Transferase Activity

1970 • 81 citations

Ganglioside GM2 storage diseases: hexosaminidase deficiencies in cultured fibroblasts.

1971 • 81 citations

Mucolipidosis III (Pseudo-Hurler Polydystrophy): Multiple Lysosomal Enzyme Abnormalities in Serum and Cultured Fibroblast Cells

1973 • 69 citations

Generalized accumulation of neutral glycosphingolipids with GM2 ganglioside accumulation in the brain

1972 • 68 citations

Complementation Analysis of Maple Syrup Urine Disease in Heterokaryons derived from Cultured Human Fibroblasts

1973 • 53 citations

Antibody against purified human hexosaminidase B cross-reacting with human hexosaminidase A

1972 • 44 citations

Uptake of beta-glucuronidase by deficient human fibroblasts.

1973 • 38 citations

TAY-SACHS DISEASE: INTERRELATION OF HEXOSAMINIDASES A AND B

1972 • 24 citations

Mucolipidosis III (Pseudo-Hurler Polydystrophy)

2006 • 21 citations

On the molecular basis of Sandhoff's disease

1973 • 20 citations

Immunological identity of human liver hexosaminidases A and B

1972 • 14 citations