Generalized accumulation of neutral glycosphingolipids with GM2 ganglioside accumulation in the brain

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

CHROMATOGRAPHlC SEPARATION OF HUMAN BRAIN GANGLIOSIDES*

1963 • 1,644 citations

Tay-Sachs Disease: Generalized Absence of a Beta-D- N -Acetylhexosaminidase Component

1969 • 707 citations

Quantitative determination of the neutral glycosyl ceramides in human blood

1967 • 662 citations

N-Acetyl-β-glucosaminidases in human spleen

1968 • 523 citations

Deficient hexosaminidase activity in an exceptional case of Tay-Sachs disease with additional storage of kidney globoside in visceral organs

1968 • 329 citations

ENZYME ALTERATIONS AND LIPID STORAGE IN THREE VARIANTS OF TAY‐SACHS DISEASE

1971 • 292 citations

Variation of β‐N‐acetylhexosaminidase‐pattern in Tay‐Sachs disease

1969 • 258 citations

Inborn Disorders of Sphingolipid Metabolism

1967 • 158 citations

Lysosomal hydrolases: Conversion of acidic to basic forms by neuraminidase

1971 • 148 citations

Demonstration of an alteration of ganglioside metabolism in Tay-Sachs disease

1969 • 133 citations

Glycolipids and other lipid constituents of normal human liver

1970 • 129 citations

Brain ceramide hexosides in Tay-Sachs disease and generalized gangliosidosis (GM1-gangliosidosis)

1967 • 118 citations

Neutral glycolipids of human kidney isolation, identification, and fatty acid composition

1966 • 102 citations

Detection and resolution of gangliosides in lipid extracts by thin-layer chromatography

1963 • 95 citations

G _M2 ‐gangliosidosis with total hexosaminidase deficiency

1971 • 93 citations

In Vivo Studies on Glycosphingolipid Metabolism in Porcine Blood

1970 • 91 citations

Partial deficiency of hexosaminidase component A in juvenile G _M2 ‐gangliosidosis

1970 • 81 citations

Neutral Glycolipids of Human Blood Serum, Spleen and Liver

1963 • 78 citations

N-ACETYLHEXOSAMINIDASE ACTIVITIES IN TAY-SACHS DISEASE

1969 • 73 citations

Mass spectrometry of neutral, mono- and disialoglycosphingolipids

1971 • 67 citations

Tay‐sachs disease and related disorders: Fractionation of brain N‐acetyl‐β‐hexosaminidase on DEAE‐cellulose

1970 • 63 citations

Composition of brain gangliosides

1961 • 54 citations

Generalized accumulation of neutral glycosphingolipids with GM2 ganglioside accumulation in the brain

1972 • 49 citations

THE METABOLISM OF GANGLIOSIDES IN CEREBRAL LIPIDOSES

1967 • 38 citations

Occurrence of hematoside in human plasma

1970 • 29 citations

THE GLYCOLIPIDS OF THE BRAIN OF TAY-SACHS' DISEASE.--THE CHEMICAL STRUCTURES OF A GLOBOSIDE AND MAIN GANGLIOSIDE.

1963 • 27 citations

A new glycolipid in Tay-Sachs brain

1961 • 20 citations

Cerebral and Visceral Glycolipids in a Case of Tay-Sachs Disease

1969 • 15 citations

THE DIAGNOSIS OF TAY‐SACHS DISEASE¹

1971 • 9 citations