Multiple Roles for Hepatocyte Growth Factor in Sympathetic Neuron Development

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Estimation of nuclear population from microtome sections

1946 • 4,378 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Scatter factor/hepatocyte growth factor is essential for liver development

1995 • 1,398 citations

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

1995 • 1,278 citations

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1994 • 1,065 citations

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

1995 • 1,039 citations

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1994 • 983 citations

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

1994 • 978 citations

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1994 • 804 citations

A BDNF autocrine loop in adult sensory neurons prevents cell death

1995 • 743 citations

Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development.

1993 • 707 citations

Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons

1996 • 403 citations

A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids

1986 • 337 citations

Vasoactive intestinal peptide regulates mitosis, differentiation and survival of cultured sympathetic neuroblasts

1990 • 317 citations

Uncoupling of Grb2 from the Met Receptor In Vivo Reveals Complex Roles in Muscle Development

1996 • 309 citations

Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.

1995 • 301 citations

Proliferation and differentiation of embryonic chick sympathetic neurons: Effects of ciliary neurotrophic factor

1989 • 297 citations

Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts.

1988 • 239 citations

Lack of Neurotrophin-3 Results in Death of Spinal Sensory Neurons and Premature Differentiation of Their Precursors

1996 • 236 citations

Hepatocyte growth factor--scatter factor: mitogen, motogen, and met.

1991 • 234 citations

Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons

1997 • 223 citations

The relationship of cell division to the acquisition of adrenergic characteristics by developing sympathetic ganglion cell precursors

1978 • 213 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

TrkA, but not TrkC, receptors are essential for survival of sympathetic neurons in vivo.

1996 • 194 citations

Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro

1996 • 187 citations

Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain.

1994 • 183 citations

Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation

1987 • 167 citations

TrkA, But Not TrkC, Receptors Are Essential for Survival of Sympathetic NeuronsIn Vivo

1996 • 162 citations

Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons.

1995 • 160 citations

Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons

1997 • 152 citations

Catecholamine biosynthetic enzymes are expressed in replicating cells of the peripheral but not the central nervous system.

1980 • 139 citations

Co-expression of theHGF/SF andc-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis

1996 • 115 citations

Neuroblast mitosis in dissociated culture: regulation and relationship to differentiation.

1990 • 113 citations

Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling

1996 • 112 citations

The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGF

1989 • 103 citations

A Local Action of Neurotrophin-3 Prevents the Death of Proliferating Sensory Neuron Precursor Cells

1996 • 101 citations

Hepatocyte Growth Factor Promotes Motor Neuron Survival and Synergizes with Ciliary Neurotrophic Factor

1997 • 100 citations

Neurotrophin switching: where does it stand?

1997 • 99 citations

Regulation of nerve growth factor receptor gene expression in sympathetic neurons during development.

1995 • 92 citations

Sympathetic neurons in neonatal rats require endogenous neurotrophin-3 for survival

1995 • 85 citations

Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos

1997 • 85 citations

Intrinsic differences in the growth rate of early nerve fibres related to target distance

1989 • 79 citations

Bcl-2 influences axonal growth rate in embryonic sensory neurons

1997 • 77 citations

DNA SYNTHESIS AND CELL DIVISION IN DIFFERENTIATING AVIAN ADRENERGIC NEUROBLASTS

1974 • 43 citations

Hepatocyte Growth Factor/Scatter Factor: Structure, Function and Regulation by Glycosaminoglycans.

1996 • 28 citations