POSSIBLE CORRELATION BETWEEN HIGH LEVELS OF IL-18 IN THE CORD BLOOD OF PRE-TERM INFANTS AND NEONATAL DEVELOPMENT OF PERIVENTRICULAR LEUKOMALACIA AND CEREBRAL PALSY

Cloning of a new cytokine that induces IFN-γ production by T cells

1995 • 2,584 citations

Interleukin-18 Regulates Both Th1 and Th2 Responses

2001 • 1,284 citations

Maternal Intrauterine Infection, Cytokines, and Brain Damage in the Preterm Newborn

1997 • 898 citations

CCR5⁺and CXCR3⁺T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions

1999 • 839 citations

Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1β, and tumor necrosis factor-α), neonatal brain white matter lesions, and cerebral palsy

1997 • 763 citations

Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia

1996 • 587 citations

Neonatal cytokines and coagulation factors in children with cerebral palsy

1998 • 563 citations

Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm singleton babies

1995 • 510 citations

Cerebral Palsy

1994 • 493 citations

Interleukin-18: A Novel Cytokine That Augments Both Innate and Acquired Immunity

1998 • 458 citations

IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

1999 • 435 citations

High expression of tumor necrosis factor-α and interleukin-6 in periventricular leukomalacia

1997 • 376 citations

IL-18 Is a Potent Coinducer of IL-13 in NK and T Cells: A New Potential Role for IL-18 in Modulating the Immune Response

1999 • 351 citations

IL-18 accounts for both TNF-alpha- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice.

1997 • 325 citations

White matter injury in the preterm infant: an important determination of abnormal neurodevelopment outcome

1998 • 217 citations

Cultures of astrocytes and microglia express interleukin 18

1999 • 184 citations

Obstetric antecedents of intraventricular hemorrhage and periventricular leukomalacia in the low-birth-weight neonate

1997 • 168 citations

Murine Microglial Cells Produce and Respond to Interleukin‐18

1999 • 153 citations

Interleukin-18 (IL-18), although anti-allergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

1999 • 151 citations

Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitis.

1998 • 147 citations

Amniotic fluid concentrations of Interleukin‐1β, Interleukin‐6 and TNF‐α in chorioamnionitis before 32 weeks of gestation: histological associations and neonatal outcome

1999 • 146 citations

Interleukin-6 in the Cerebrospinal Fluid After Perinatal Asphyxia Is Related to Early and Late Neurological Manifestations

1997 • 140 citations

Elevation of plasma interleukin‐18 concentration is correlated with disease activity in systemic lupus erythematosus

2000 • 122 citations

Ischemia/reperfusion-induced IFN-gamma up-regulation: involvement of IL-12 and IL-18.

1999 • 121 citations

Neutralizing Antibodies to IFN-γ-Inducing Factor Prevent Experimental Autoimmune Encephalomyelitis

1998 • 117 citations

Risk factors and determinants of neurodevelopmental outcome in cystic periventricular leucomalacia

2000 • 114 citations

Interferons and cerebral palsy

1999 • 108 citations

Participation of the novel cytokine interleukin 18 in the host response to intra-amniotic infection

2000 • 91 citations

Ischemia/Reperfusion-Induced IFN-γ Up-Regulation: Involvement of IL-12 and IL-18

1999 • 86 citations

IL-18 in pregnancy; the elevation of IL-18 in maternal peripheral blood during labour and complicated pregnancies

2000 • 81 citations

Interferon-γ–inducing factor (IL-18) and interferon-γ in inflammatory CNS diseases

1999 • 73 citations

Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary study

1999 • 67 citations