Fibroblast Growth Factor-2 (FGF-2) and Platelet-Derived Growth Factor AB (PDGFAB) Promote Adult SVZ-Derived Oligodendrogenesis in Vivo

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

CNS stem cells express a new class of intermediate filament protein

1990 • 3,138 citations

Long-Distance Neuronal Migration in the Adult Mammalian Brain

1994 • 2,291 citations

Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain

1997 • 1,878 citations

Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

1999 • 1,872 citations

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

1994 • 1,400 citations

Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.

1993 • 1,319 citations

Neurogenesis in the Neocortex of Adult Primates

1999 • 1,268 citations

Multipotent CNS Stem Cells Are Present in the Adult Mammalian Spinal Cord and Ventricular Neuroaxis

1996 • 1,209 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Induction of neurogenesis in the neocortex of adult mice

2000 • 1,201 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

The Adult Rat Hippocampus Contains Primordial Neural Stem Cells

1997 • 1,080 citations

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

1996 • 1,027 citations

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

1995 • 1,014 citations

Embryonic Stem Cell-Derived Glial Precursors: A Source of Myelinating Transplants

1999 • 981 citations

Cell replacement therapies for central nervous system disorders

2000 • 948 citations

Premyelinating Oligodendrocytes in Chronic Lesions of Multiple Sclerosis

2002 • 941 citations

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain

1996 • 757 citations

NG2-Positive Oligodendrocyte Progenitor Cells in Adult Human Brain and Multiple Sclerosis Lesions

2000 • 686 citations

bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells

1993 • 651 citations

Chronic Stage Multiple Sclerosis Lesions Contain a Relatively Quiescent Population of Oligodendrocyte Precursor Cells

1998 • 551 citations

Endogenous Progenitors Remyelinate Demyelinated Axons in the Adult CNS

1997 • 539 citations

Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination

1999 • 536 citations

Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells

1993 • 441 citations

PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage

1992 • 435 citations

Postmitotic death is the fate of constitutively proliferating cells in the subependymal layer of the adult mouse brain

1992 • 393 citations

Stimulation of Neonatal and Adult Brain Neurogenesis by Subcutaneous Injection of Basic Fibroblast Growth Factor

1999 • 375 citations

Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord

1998 • 342 citations

Embryonic (PSA) N‐CAM reveals chains of migrationg neuroblasts between the lateral ventricle and the olfactory bulb of adult mice

1995 • 336 citations

A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM.

1986 • 314 citations

Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: An immunohistochemical study

1992 • 309 citations

Activation and Proliferation of Endogenous Oligodendrocyte Precursor Cells during Ethidium Bromide-Induced Demyelination

1999 • 273 citations

Cell and molecular analysis of the developing and adult mouse subventricular zone of the cerebral hemispheres

1995 • 271 citations

Neurogenesis persists in the subependymal layer of the adult mouse brain

1993 • 262 citations

Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts

1993 • 259 citations

Identification, Isolation, and Promoter-Defined Separation of Mitotic Oligodendrocyte Progenitor Cells from the Adult Human Subcortical White Matter

1999 • 250 citations

Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity

1999 • 215 citations

Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease

1995 • 211 citations

Adult-derived neural precursors transplanted into multiple regions in the adult brain

1999 • 199 citations

Adult Nestin‐expressing Subependymal Cells Differentiate to Astrocytes in Response to Brain Injury

1997 • 178 citations

Generation of oligodendroglial progenitors in acute inflammatory demyelinating lesions of the rat brain stem is associated with demyelination rather than inflammation.

1999 • 174 citations

Cortical lesions induce an increase in cell number and PSA-NCAM expression in the subventricular zone of adult rats

1996 • 149 citations

Mitogen and Substrate Differentially Affect the Lineage Restriction of Adult Rat Subventricular Zone Neural Precursor Cell Populations

1999 • 145 citations

Myelination of the canine central nervous system by glial cell transplantation: A model for repair of human myelin disease

1997 • 142 citations

Peptides crossing the blood–brain barrier: some unusual observations

1999 • 140 citations

Intraspinal Delivery of Neurotrophin-3 Using Neural Stem Cells Genetically Modified by Recombinant Retrovirus

1999 • 136 citations

Survival and differentiation of oligodendrocytes from neural tissue transplanted into new-born mouse brain

1983 • 132 citations

Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice

2001 • 114 citations

Developmental Expression of Platelet-Derived Growth Factor α-Receptor in Neurons and Glial Cells of the Mouse CNS

1997 • 110 citations

Early recruitment of oligodendrocyte precursors in CNS demyelination

1994 • 109 citations

Expansion of rat oligodendrocyte progenitors into proliferative ?oligospheres? that retain differentiation potential

1996 • 100 citations

Platelet‐derived growth factor is a survival factor for PSA‐NCAM + oligodendrocyte pre‐progenitor cells

1995 • 95 citations

Penetration of neurotrophins and cytokines across the blood–brain/blood–spinal cord barrier

1999 • 94 citations

Differentiation of oligodendroglial progenitors derived from cortical multipotent cells requires extrinsic signals including activation of gp130/LIFbeta receptors.

1998 • 85 citations

Basic fibroblast growth factor prolongs the proliferation of rat cortical progenitor cells in vitro without altering their cell cycle parameters

1997 • 80 citations

Transplantation of Human Embryonic Oligodendrocytes into Shiverer Brain^a

1987 • 78 citations

Intraventricular transplantation of oligodendrocyte progenitors into a fetal myelin mutant results in widespread formation of myelin

1999 • 77 citations

Migration and Multipotentiality of PSA-NCAM+ Neural Precursors Transplanted in the Developing Brain

2001 • 76 citations

Tracing transplanted oligodendrocytes during migration and maturation in the shiverer mouse brain

1991 • 72 citations

Increased proliferation of precursor cells in the adult rat brain after targeted lesioning

1996 • 63 citations

The response of adult oligodendrocyte progenitors to demyelination in EAE

2001 • 60 citations

To what extent is oligodendrocyte progenitor migration a limiting factor in the remyelination of multiple sclerosis lesions?

1997 • 58 citations

EGF Infusion Stimulates the Proliferation and Migration of Embryonic Progenitor Cells Transplanted in the Adult Rat Striatum

2000 • 57 citations

Transplanted Transgenically Marked Oligodendrocytes Survive, Migrate and Myelinate in the Normal Mouse Brain as They Do in the Shiverer Mouse Brain

1994 • 52 citations

Mouse oligospheres: From pre-progenitors to functional oligodendrocytes

1999 • 52 citations

Platelet-Derived Growth Factor Receptor-α in Ventricular Zone Cells and in Developing Neurons

2001 • 48 citations

Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation

1995 • 43 citations

The ultrastructure of isolated rat oligodendroglial cell cultures

1982 • 33 citations

Storage, metabolism, and processing of 125I-fibroblast growth factor-2 after intracerebral injection

1994 • 29 citations

Retroviral-mediated transfer of the galactocerebrosidase gene in neural progenitor cells

1998 • 26 citations

Ex vivo gene delivery of platelet-derived growth factor increases 0-2A progenitors in adult rat spinal cord.

1996 • 24 citations

Do central nervous system axons remyelinate?

2000 • 12 citations

X-irradiation-induced loss of O-2A progenitor cells in rat spinal cord is inhibited by implants of cells engineered to secrete glial growth factor 2

1999 • 8 citations