Formation of S-[2-(N7-guanyl)ethyl] adducts by the postulated S-(2-chloroethyl)cysteinyl and S-(2-chloroethyl)glutathionyl conjugates of 1,2-dichloroethane

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

1963 • 801 citations

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro

1978 • 247 citations

Episulfonium ions: myth and reality

1979 • 176 citations

Evidence for formation of an S-[2-(N7-guanyl)ethyl]glutathione adduct in glutathione-mediated binding of the carcinogen 1,2-dibromoethane to DNA.

1983 • 150 citations

S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane

1986 • 104 citations

Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione.

1986 • 91 citations

Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)glutathione and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine, the glutathione and cysteine conjugates of chlorotrifluoroethene.

1985 • 77 citations

Cysteine conjugate beta-lyase.

1983 • 67 citations

Cysteine Conjugate β-Lyase

1980 • 61 citations

The bioactivation of 1,2-dibromoethane in rat hepatocytes: covalent binding to nucleic acids

1982 • 48 citations

Repair of rat liver DNA in vivo damaged by ethylene dibromide

1977 • 43 citations

Stabilities of 7-alkylguanosines and 7-deoxyguanosines formed by phosphoramide mustard and nitrogen mustard

1986 • 30 citations

An investigation of the role of microsomal oxidative metabolism in the in vivo genotoxicity of 1,2-dichloroethane

1985 • 28 citations

The hydrolysis and alkylation activities of S-(2-haloethyl)-l-cysteine analogs—Evidence for extended half-life

1983 • 26 citations