Does Nitric Oxide Regulate Smooth Muscle Cell Proliferation?

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis

1992 • 4,765 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension

1990 • 2,388 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium.

1983 • 1,441 citations

Inhibition of Neointimal Smooth Muscle Accumulation After Angioplasty by an Antibody to PDGF

1991 • 1,081 citations

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1991 • 813 citations

Biochemical Evidence for Impaired Nitric Oxide Synthesis in Patients With Peripheral Arterial Occlusive Disease

1997 • 501 citations

Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP

1994 • 467 citations

Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery.

1989 • 420 citations

Nitric Oxide Reversibly Inhibits the Migration of Cultured Vascular Smooth Muscle Cells

1996 • 412 citations

p53 expression in nitric oxide‐induced apoptosis

1994 • 403 citations

Nitric oxide released from activated platelets inhibits platelet recruitment.

1997 • 388 citations

Vasoactive Substances Regulate Vascular Smooth Muscle Cell Apoptosis

1996 • 345 citations

Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine.

1994 • 330 citations

S‐nitroso‐glutathione inhibits platelet activation in vitro and in vivo

1992 • 330 citations

Four weeks of cycle training increases basal production of nitric oxide from the forearm

1997 • 290 citations

Kinetics of vein graft hyperplasia: Association with tangential stress

1987 • 287 citations

Randomized, Double-Blind, Placebo-Controlled Study of Supplemental Oral <scp>l</scp> -Arginine in Patients With Heart Failure

1996 • 278 citations

Nitric Oxide–Generating Compounds Inhibit Total Protein and Collagen Synthesis in Cultured Vascular Smooth Muscle Cells

1995 • 273 citations

THE VASCULAR BIOLOGY OF NITRIC OXIDE AND ITS ROLE IN ATHEROGENESIS

1996 • 256 citations

Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. PGH2 does not contribute to impaired endothelium-dependent relaxation.

1994 • 255 citations

Inhibition by nitric oxide and nitric oxide-producing vasodilators of DNA synthesis in vascular smooth muscle cells

1990 • 239 citations

Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide.

1995 • 229 citations

L-Arginine Inhibits Balloon Catheter-Induced Intimal Hyperplasia

1993 • 223 citations

cGMP-Elevating Agents Suppress Proliferation of Vascular Smooth Muscle Cells by Inhibiting the Activation of Epidermal Growth Factor Signaling Pathway

1997 • 208 citations

Nitric Oxide Toxicity in Islet Cells Involves Poly(ADP-Ribose) Polymerase Activation and Concomitant NAD+ Depletion

1994 • 188 citations

Quenching of the tyrosyl free radical of ribonucleotide reductase by nitric oxide. Relationship to cytostasis induced in tumor cells by cytotoxic macrophages.

1994 • 187 citations

Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury.

1994 • 177 citations

Persistent dysfunction of regenerated endothelium after balloon angioplasty of rabbit iliac artery.

1990 • 175 citations

Dietary l-Arginine Supplementation Normalizes Platelet Aggregation in Hypercholesterolemic Humans

1997 • 175 citations

Platelet-derived growth factor suppresses and fibroblast growth factor enhances cytokine-induced production of nitric oxide by cultured smooth muscle cells. Effects on cell proliferation.

1992 • 172 citations

Heparin selectively inhibits a protein kinase C-dependent mechanism of cell cycle progression in calf aortic smooth muscle cells [published erratum appears in J Cell Biol 1990 Mar;110(3):863]

1989 • 170 citations

Induction of the Cyclin-dependent Kinase Inhibitor p21 by Nitric Oxide-generating Vasodilator in Vascular Smooth Muscle Cells

1997 • 165 citations

Balloon injury and interleukin-1 beta induce nitric oxide synthase activity in rat carotid arteries.

1992 • 139 citations

Antiproliferative action of cyclic GMP-elevating vasodilators in cultured rabbit aortic smooth muscle cells

1989 • 138 citations

Accumulation of endogenous inhibitors for nitric oxide synthesis and decreased content of L‐arginine in regenerated endothelial cells

1995 • 131 citations

Expression of Inducible Nitric Oxide Synthase Inhibits Platelet Adhesion and Restores Blood Flow in the Injured Artery

1996 • 128 citations

Local Intramural Delivery of <scp>l</scp> -Arginine Enhances Nitric Oxide Generation and Inhibits Lesion Formation After Balloon Angioplasty

1997 • 118 citations

Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques.

1995 • 117 citations

Nitric oxide decreases cytosolic free calcium in Balb/c 3T3 fibroblasts by a cyclic GMP-independent mechanism.

1991 • 115 citations

Cell cycle-dependent inhibition of human vascular smooth muscle cell proliferation by prostaglandin E1

1985 • 115 citations

Effect of Endogenous Nitric Oxide on Mitochondrial Respiration of Rat Hepatocytes In Vitro and In Vivo

1991 • 114 citations

Chronic Inhalation of Nitric Oxide Inhibits Neointimal Formation After Balloon-Induced Arterial Injury

1996 • 113 citations

Effect of the Direct Nitric Oxide Donors Linsidomine and Molsidomine on Angiographic Restenosis After Coronary Balloon Angioplasty

1997 • 113 citations

L-arginine improves endothelium-dependent vasorelaxation and reduces intimal hyperplasia after balloon angioplasty.

1994 • 101 citations

Cell cycle effects of nitric oxide on vascular smooth muscle cells

1997 • 93 citations

Induction of a macrophage-like nitric oxide synthase in cultured rat aortic endothelial cells. IL-1 beta-mediated induction regulated by tumor necrosis factor-alpha and IFN-gamma.

1993 • 92 citations

CD4+ mononuclear cells induce cytokine expression, vascular smooth muscle cell proliferation, and arterial occlusion after endothelial injury.

1994 • 91 citations

Beneficial effect of SPM-5185, a cysteine-containing nitric oxide donor, in rat carotid artery intimal injury.

1994 • 81 citations

Balloon catheter de-endothelialization of the nude rat carotid. Response to injury in the absence of functional T lymphocytes.

1991 • 78 citations

Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells

1994 • 77 citations

Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits

1996 • 72 citations

Reduction of experimental vein graft intimal hyperplasia and preservation of nitric oxide-mediated relaxation by the nitric oxide precursor L-arginine.

1994 • 68 citations

FK409, a new nitric-oxide donor, suppresses smooth muscle proliferation in the rat model of balloon angioplasty

1995 • 64 citations

Dual cell cycle-specific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells

1997 • 57 citations

Nitric oxide blocks the cell cycle of mouse macrophage‐like cells in the early G₂+M phase

1994 • 47 citations

Kinetics of vein graft hyperplasia: Association with tangential stress

1987 • 37 citations

Effects of non-insulin dependent diabetes mellitus on the reactivity of human internal mammary artery and human saphenous vein

1995 • 35 citations

NO increases protein tyrosine phosphatase activity in smooth muscle cells: relationship to antimitogenesis

1997 • 29 citations

Role of nitric oxide in the effect of blood flow on neointima formation

1996 • 26 citations

NG-Nitro-L-arginine Methyl Ester Does Not Affect Balloon Catheter-Induced Intimal Hyperplasia in Rats

1993 • 12 citations

Cell proliferation in human arteries

1992 • 2 citations