Lymphoid cells transformed by Abelson virus require the v-abl protein-tyrosine kinase only during early G1.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Oncogenes and signal transduction

1991 • 2,816 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1991 • 1,901 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1989 • 1,252 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1991 • 1,190 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine.

1983 • 978 citations

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

Death in Embryonic Systems

1966 • 943 citations

Programmed cell death: Apoptosis and oncogenesis

1991 • 856 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1990 • 767 citations

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1987 • 670 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

The platelet-derived growth factor

1978 • 649 citations

2,3,7,8-Tetrachlorodibenzo- p -Dioxin Kills Immature Thymocytes by Ca ²⁺ -Mediated Endonuclease Activation

1988 • 460 citations

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1989 • 427 citations

Colony-stimulating factor-1 receptor

1990 • 362 citations

Leukemia and the disruption of normal hematopoiesis

1991 • 357 citations

Molecular and cellular origins of B lymphocyte diversity

1991 • 346 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

Altered phosphorylation and activation of PP60c-src during fibroblast mitosis

1988 • 249 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores.

1990 • 226 citations

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants.

1991 • 224 citations

Cell Cycle—Regulated Binding of c-Abl Tyrosine Kinase to DNA

1992 • 202 citations

Oncogenic potential of bcl-2 demonstrated by gene transfer

1988 • 180 citations

Death by suicide: one way to go in mammalian cellular development?

1991 • 167 citations

Differential Phosphorylation of c-Abl in Cell Cycle Determined by cdc 2 Kinase and Phosphatase Activity

1990 • 157 citations

the Viral and Cellular Forms of the Abelson (Dbl) Oncogene

1988 • 157 citations

Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies.

1988 • 121 citations

Lymphoma models for B cell activation and tolerance. III. Cell cycle dependence for negative signalling of WEHI-231 B lymphoma cells by anti-mu.

1986 • 112 citations

Progression of the transformed phenotype in clonal lines of Abelson virus-infected lymphocytes.

1983 • 71 citations

Phosphorylation of Cellular Proteins in Rous Sarcoma Virus-Infected Cells: Analysis by Use of Anti-Phosphotyrosine Antibodies

1988 • 54 citations

Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesis.

1987 • 38 citations

Activation of Phosphatidylinositol 3-Kinase in Cells Expressing abl Oncogene Variants

1991 • 35 citations

Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity

1990 • 33 citations

Multiple steps are required for the induction of tumors by Abelson murine leukemia virus

1989 • 32 citations

Progression of the Transformed Phenotype in Clonal Lines of Abelson Virus-Infected Lymphocytes

1983 • 31 citations

Hyperexpression of Interleukin-7 Is Not Necessary or Sufficient for Transformation of a Pre-B Lymphoid Cell Line

1991 • 30 citations

Notes: bcr/abl and src but Not myc and ras Replace v-abl in Lymphoid Transformation

1990 • 25 citations

The effects of bacterial lipopolysaccharide, anti‐receptor antibodies and recombinant interferon on mouse B cell cycle progression using 5‐bromo‐2'‐deoxyuridine/hoechst 33258 dye flow cytometry

1989 • 19 citations