The protein kinase A-regulated cardiac CI− channel resembles the cystic fibrosis transmembrane conductance regulator

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1990 • 85,659 citations

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1979 • 22,482 citations

Genomic sequencing.

1984 • 8,343 citations

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1989 • 7,327 citations

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

1991 • 1,108 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 658 citations

A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase.

1986 • 581 citations

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

1991 • 564 citations

Generation of cAMP-Activated Chloride Currents by Expression of CFTR

1991 • 550 citations

Nucleoside triphosphates are required to open the CFTR chloride channel

1991 • 520 citations

Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

1991 • 508 citations

Acceleration of nucleic acid hybridization rate by polyethylene glycol

1986 • 383 citations

Regulation and deregulation of cardiac Na+–Ca2+ exchange in giant excised sarcolemmal membrane patches

1990 • 320 citations

Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture

1980 • 306 citations

Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes

1989 • 271 citations

Autonomic Regulation of a Chloride Current in Heart

1989 • 254 citations

Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel.

1991 • 251 citations

Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin

1991 • 171 citations

The sodium pump : recent developments

1991 • 151 citations

Chloride current in mammalian cardiac myocytes. Novel mechanism for autonomic regulation of action potential duration and resting membrane potential.

1990 • 146 citations

Chloride‐sensitive nature of the adrenaline‐induced current in guinea‐pig cardiac myocytes.

1990 • 121 citations

Q-T interval syndromes

1974 • 119 citations

Is the mammalian cell plasma membrane a barrier to oxygen transport?

1992 • 100 citations

cAMP-activated Cl channels in CFTR-transfected cystic fibrosis pancreatic epithelial cells

1992 • 94 citations

Anion channels activated by adrenaline in cardiac myocytes

1990 • 90 citations

Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.

1992 • 70 citations

Supraventricular Tachycardia in Patients with Cystic Fibrosis

1986 • 18 citations

Cardiac Involvement in Cystic Fibrosis Revealed by a Ventricular Arrhythmia

1984 • 17 citations