Modulation of Motility and Proliferation of Glioma Cells by Hepatocyte Growth Factor

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops.

1992 • 689 citations

Emerging Multipotent Aspects of Hepatocyte Growth Factor

1996 • 662 citations

The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis.

1995 • 578 citations

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

1992 • 577 citations

Expression of the Met/HGF receptor in normal and neoplastic human tissues.

1991 • 481 citations

Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

1993 • 467 citations

National survey of patterns of care for brain-tumor patients

1989 • 385 citations

Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII

1993 • 373 citations

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues.

1990 • 333 citations

Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues.

1991 • 316 citations

RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP.

1994 • 311 citations

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors

1994 • 304 citations

Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

1993 • 281 citations

Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.

1996 • 228 citations

cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases.

1994 • 202 citations

Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro

1996 • 187 citations

Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor

1995 • 185 citations

Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain.

1994 • 183 citations

Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor

1991 • 179 citations

Prognostic significance of Ki-67 labeling indices obtained using MIB-1 monoclonal antibody in patients with supratentorial astrocytomas

1996 • 174 citations

Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo.

1994 • 158 citations

Control of human glioma cell growth, migration and invasion in vitro by transforming growth factor β1

1994 • 150 citations

Invasion of experimental rat brain tumor: early morphological changes following microinjection of C6 glioma cells

1993 • 140 citations

Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture.

1995 • 138 citations

Expression of Local Hepatocyte Growth Factor System in Vascular Tissues

1995 • 135 citations

Scatter factor expression and regulation in human glial tumors

1996 • 121 citations

Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor.

1994 • 107 citations

Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme.

1994 • 104 citations

Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells.

1994 • 102 citations

Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors.

1994 • 86 citations

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF‐α, bFGF, IL‐2] on glioma spheroid growth, migration and invasion

1994 • 84 citations

Oncogene amplification in human gliomas: a molecular cytogenetic analysis.

1994 • 84 citations

Neuronal proteoglycans: biosynthesis and functional interaction with neurons in vitro

1988 • 78 citations

Extraneural Metastases in Gliosarcoma: A Case Report and Review of the Literature

1985 • 77 citations

Concomitant expression of hepatocyte growth factor (HGF), HGF activator and c‐met genes in human glioma cells in vitro

1995 • 73 citations

Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues

1994 • 68 citations

Scatter factor (hepatocyte growth factor) is a potent angiogenesis factor in vivo.

1993 • 68 citations

Selective expression of the Met/HGF receptor in human central nervous system microglia.

1993 • 67 citations

The in vitro motility of human gliomas increases with increasing grade of malignancy

1995 • 64 citations

Mediation of renal cyst formation by hepatocyte growth factor

1994 • 63 citations

Altered expression and distribution of heparan sulfate proteoglycans in human gliomas.

1989 • 58 citations

Effects of hepatocyte growth factor (HGF) on human glioma cellsin vitro: HGF acts as a motility factor in glioma cells

1996 • 47 citations

Tumoral invasion in the central nervous system

1993 • 41 citations

Dual Pathways to Tubular Morphogenesis of Vascular Endothelial Cells by Human Glioma Cells: Vascular Endothelial Growth Factor/Basic Fibroblast Growth Factor and Interleukin‐8

1995 • 40 citations

Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors

1994 • 37 citations

The Incidence of Interhemispheric Extension of Glioblastoma Multiforme through the Corpus Callosum

1946 • 35 citations

Invasive glioma cells in tissue culture.

1990 • 33 citations

Amplified met gene linked to double minutes in human glioblastoma

1993 • 32 citations

Factors influencing tumor cell traffic in the central nervous system

1993 • 8 citations

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