Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1989 • 1,912 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Mammary plasminogen activator: correlation with involution, hormonal modulation and comparison between normal and neoplastic tissue

1979 • 437 citations

The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin.

1986 • 391 citations

Plasminogen Activator Release at the Neuronal Growth Cone

1981 • 388 citations

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA).

1991 • 347 citations

Directed Plasminogen Activation at the Surface of Normal and Malignant Cells

1991 • 291 citations

Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells.

1987 • 286 citations

Identification and primary sequence of an unspliced human urokinase poly(A)+ RNA.

1984 • 229 citations

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells.

1988 • 223 citations

The human urokinase-plasminogen activator gene and its promoter

1985 • 211 citations

Metastatic tumor cell interactions with endothelium, basement membrane and tissue

1989 • 157 citations

Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas.

1987 • 136 citations

Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate.

1988 • 91 citations

Suppression of urokinase-type plasminogen activator mRNA levels in human fibrosarcoma cells and synovial fibroblasts by anti-inflammatory glucocorticoids.

1986 • 85 citations

Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). Modulation by glucocorticoids.

1986 • 82 citations

Plasminogen activator activity and molecular weight patterns in human brain tumors

1988 • 45 citations

Plasminogen activating enzyme in cultured glioblastoma cells. An immunofluorescence study with monoclonal antibody.

1982 • 41 citations

Decreased urokinase receptor expression by overexpression of the plasminogen activator in a colon cancer cell line

1992 • 14 citations