Relevance for Neurobiology and Neurooncology of Antigens of Malignant Gliomas As Defined by Monoclonal Antibodiesa

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185

1986 • 1,020 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Identification of an Amplified, Highly Expressed Gene in a Human Glioma

1987 • 671 citations

GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody.

1982 • 579 citations

Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma.

1985 • 566 citations

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells

1982 • 507 citations

Heterogeneity of Genotypic and Phenotypic Characteristics of Fifteen Permanent Cell Lines Derived from Human Gliomas

1981 • 487 citations

Extracellular matrix.

1981 • 471 citations

Growth Inhibition of Human Tumor Cells in Athymic Mice by Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies

1984 • 443 citations

Chick myotendinous antigen. I. A monoclonal antibody as a marker for tendon and muscle morphogenesis.

1984 • 435 citations

Cytotactin, an extracellular matrix protein of neural and non-neural tissues that mediates glia-neuron interaction.

1985 • 391 citations

Human glioma-mesenchymal extracellular matrix antigen defined by monoclonal antibody.

1983 • 370 citations

Monoclonal antibodies to a glycolipid antigen on human neuroblastoma cells.

1985 • 317 citations

Site-restricted expression of cytotactin during development of the chicken embryo.

1986 • 302 citations

Immunohistochemical demonstration of neuron-specific enolase in neoplasms of the CNS and other tissues.

1984 • 300 citations

A six-armed oligomer isolated from cell surface fibronectin preparations

1984 • 274 citations

Identification of a human neuroectodermal tumor antigen (OFA-I-2) as ganglioside GD2.

1982 • 242 citations

Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth.

1987 • 242 citations

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen.

1986 • 231 citations

Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients.

1987 • 224 citations

A monoclonal antibody recognizes an O-acylated sialic acid in a human melanoma-associated ganglioside.

1984 • 222 citations

Regression of cutaneous metastatic melanoma by intralesional injection with human monoclonal antibody to ganglioside GD2.

1986 • 220 citations

Characterization of a human melanoma-associated ganglioside antigen defined by a monoclonal antibody, 4.2.

1982 • 217 citations

Immunobiology of primary intracranial tumors

1977 • 210 citations

Development of primary and secondary immune responses to mouse monoclonal antibodies used in the diagnosis and therapy of malignant neoplasms.

1986 • 209 citations

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

1985 • 205 citations

Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells.

1984 • 198 citations

Immunobiology of primary intracranial tumors

1977 • 191 citations

Establishment and Characterization of the Human Medulloblastoma Cell Line and Transplantable Xenograft D283 Med

1985 • 182 citations

Ganglioside GM2 as a human tumor antigen (OFA-I-1).

1983 • 174 citations

Syngeneic monoclonal antibody against melanoma antigen with interspecies cross-reactivity recognizes GM3, a prominent ganglioside of B16 melanoma.

1985 • 171 citations

Definition of a Thy-1 determinant on human neuroblastoma, glioma, sarcoma, and teratoma cells with a monoclonal antibody.

1982 • 167 citations

Reversible Osmotic Blood-Brain Barrier Disruption in Humans

1980 • 163 citations

Growth and Chemotherapeutic Response in Athymic Mice of Tumors Arising from Human Glioma-derived Cell Lines

1981 • 160 citations

Biological characterization and clinical applications of a monoclonal antibody recognizing an antigen restricted to neuroectodermal tissues

1983 • 143 citations

Collected Studies on Immunity

1907 • 140 citations

Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations

1986 • 139 citations

Antibody guided irradiation of brain glioma by arterial infusion of radioactive monoclonal antibody against epidermal growth factor receptor and blood group A antigen.

1985 • 134 citations

Sialosyllactotetraosylceramide, a novel ganglioside antigen detected in human carcinomas by a monoclonal antibody

1985 • 125 citations

Lipid composition of human neural tumors.

1979 • 125 citations

Monoclonal antibody A2B5 reacts with many gangliosides in neuronal tissue

1984 • 125 citations

Relationship of in Vitro Morphologic and Growth Characteristics of Established Human Glioma-derived Cell Lines to Their Tumorigenicity in Athymic Nude Mice

1981 • 122 citations

Gangliosides of Human Cerebral Astrocytomas

1980 • 114 citations

Strong antitumor activities of IgG3 antibodies to a human melanoma-associated ganglioside.

1985 • 112 citations

High-molecular-weight glycoproteins of human teratocarcinoma defined by monoclonal antibodies to carbohydrate determinants.

1985 • 109 citations

Chemical structure of carcinoma ganglioside antigens defined by monoclonal antibody C-50 and some allied gangliosides of human pancreatic adenocarcinoma

1985 • 101 citations

Biology of Gliomas

1981 • 96 citations

A murine monoclonal antibody detecting N-acetyl- and N-glycolyl-GM2: characterization of cell surface reactivity.

1986 • 86 citations

Demonstration of complex antigenic heterogeneity in a human glioma cell line and eight derived clones by specific monoclonal antibodies.

1983 • 85 citations

Identification of an interferon-gamma response region 5' of the human histocompatibility leukocyte antigen DR alpha chain gene which is active in human glioblastoma multiforme lines.

1987 • 78 citations

USE OF MONOCLONAL ANTIBODY PANEL TO IDENTIFY MALIGNANT CELLS IN CEREBROSPINAL FLUID

1984 • 77 citations

Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line

1986 • 70 citations

Response of glioma cells to interferon‐gamma: increase in class II RNA, protein and mixed lymphocyte reaction‐stimulating ability

1985 • 70 citations

Antigenic Heterogeneity of Human Anaplastic Gliomas and Glioma-derived Cell Lines Defined by Monoclonal Antibodies

1985 • 65 citations

A novel disialoganglioside (IV3NeuAcIII6NeuAcLc4) of human adenocarcinoma and the monoclonal antibody (FH9) defining this disialosyl structure

1986 • 63 citations

Expression of common acute lymphoblastic leukemia antigen (CALLA) on human malignant melanoma cell lines.

1983 • 62 citations

Radioimmunodetection of human glioma xenografts by monoclonal antibody to epidermal growth factor receptor.

1987 • 53 citations

Potential ganglioside antigens associated with human gliomas

1986 • 50 citations

Markers Of Human Neuroectodermal Tumors

1986 • 47 citations

Comparison of various methods for delivering radiolabeled monoclonal antibody to normal rat brain

1984 • 45 citations

The Immunohistochemical Application of Three Anti-GFAP Monoclonal Antibodies to Formalin-fixed, Paraffin-embedded, Normal and Neoplastic Brain Tissues

1986 • 43 citations

The immunobiology of human gliomas

1985 • 43 citations

Biology of Gliomas

1981 • 40 citations

A rapidly dividing human medulloblastoma cell line (D283 MED) expresses all three neurofilament subunits.

1987 • 38 citations

Comparative localization of glioma-reactive monoclonal antibodies in vivo in an athymic mouse human glioma xenograft model

1987 • 36 citations

DNA Content and Chromosomal Composition of Malignant Human Gliomas

1985 • 32 citations

Monoclonal antibodies reactive with epitopes restricted to glial fibrillary acidic proteins of several species

1983 • 32 citations

The Potential of Monoclonal Antibodies as Carriers of Radiation and Drugs for Immunodetection and Therapy of Brain Tumors

2015 • 30 citations

Reactivity of anti-human brain serum with human lymphocytes.

1977 • 26 citations

Production and characterization of two human glioma xenograft-localizing monoclonal antibodies.

1986 • 23 citations

Mouse monoclonal antibodies with specificity for the melanoma-associated ganglioside disialyllactosylceramide (GD3) also react with the structural analogue disialylparagloboside

1985 • 19 citations

The Characterisation of Gliomas Using Human Monoclonal Antibodies

1984 • 9 citations

Immunolocalisation of Human Brain Tumours

1986 • 6 citations