An in vitro autoradiographic analysis of mu and delta opioid binding in the hippocampal formation of kindled rats

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

GABA in nervous system function

1977 • 1,087 citations

A new method for receptor autoradiography: [3H]Opioid receptors in rat brain

1979 • 797 citations

Opioid Peptides May Excite Hippocampal Pyramidal Neurons by Inhibiting Adjacent Inhibitory Interneurons

1979 • 610 citations

Quantitative receptor autoradiography using [3H]Ultrofilm: application to multiple benzodiazepine receptors

1982 • 529 citations

Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography.

1980 • 463 citations

Multiple opiate receptors: different regional distribution in the brain and differential binding of opiates and opioid peptides.

1979 • 399 citations

Morphine and Enkephalin: Analgesic and Epileptic Properties

1977 • 358 citations

Comparison of the Distribution of Dynorphin Systems and Enkephalin Systems in Brain

1982 • 278 citations

Novel opiate binding sites selective for benzomorphan drugs.

1981 • 225 citations

Epileptic properties of leucine- and methionine-enkephalin: Comparison with morphine and reversibility by naloxone

1978 • 208 citations

beta-Endorphin induces nonconvulsive limbic seizures.

1978 • 192 citations

The kindling model of epilepsy: a critical review.

1985 • 186 citations

In vitro autoradiography of opiate receptors in rat brain suggests loci of "opiatergic" pathways.

1980 • 181 citations

gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study

1985 • 164 citations

Endogenous opiods may mediate post-ictal behavioral depression in amygdaloid-kindled rats

1979 • 156 citations

Potent morphiceptin analogs: structure activity relationships and morphine-like activities.

1983 • 138 citations

Opioid peptides induce reduction of enkephalin receptors in cultured neuroblastoma cells

1982 • 130 citations

Electrophysiological interactions of enkephalins with neuronal circuitry in the rat hippocampus. II. Effects on interneuron excitability

1980 • 127 citations

Loss of opiate receptor activity in neuroblastoma X glioma NG108-15 hybrid cells after chronic opiate treatment. A multiple-step process.

1982 • 122 citations

Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling

1986 • 113 citations

Changes of hippocampal Met-enkephalin content after recurrent motor seizures

1980 • 110 citations

Amygdaloid kindling enhances the enkephalin content in the rat brain

1981 • 108 citations

Repeated electroconvulsive shock or chronic morphine treatment increases the number of 3HDALA2, DLEU5enkephalin binding sites in rat brain membranes

1982 • 106 citations

The epileptogenic spectrum of opiate agonists

1982 • 103 citations

Possible mechanisms of enkephalin action on hippocampal CA1 pyramidal neurons

1981 • 96 citations

ALTERATIONS IN GABA METABOLISM AND MET‐ENKEPHALIN CONTENT IN RAT BRAIN FOLLOWING REPEATED ELECTROCONVULSIVE SHOCKS

1978 • 88 citations

Dynorphin- and enkephalin-like immunoreactivity is altered in limbic-basal ganglia regions of rat brain after repeated electroconvulsive shock.

1986 • 82 citations

Anticonvulsants Specific for Petit Mal Antagonize Epileptogenic Effect of Leucine Enkephalin

1980 • 81 citations

Quantitative autoradiographic analysis of Mu and delta opioid binding sites in the rat hippocampal formation

1986 • 80 citations

Muscarinic cholinergic receptors participate in the kindling model of epilepsy

1978 • 77 citations

Dynorphin- and enkephalin-like immunoreactivity is altered in limbic- basal ganglia regions of rat brain after repeated electroconvulsive shock

1986 • 75 citations

Down regulation of δ but not μ opioid receptors in the hippocampal slice associated with loss of physiological response

1983 • 60 citations

Modification of kindled amygdaloid seizures by opiate agonists and antagonists.

1984 • 58 citations

Naloxone facilitates amygdaloid kindling in rats

1980 • 57 citations

Opioid‐induced epileptogenic phenomena: Anatomical, behavioral, and electroencephalographic features

1984 • 53 citations

Ontogeny of opiate binding sites in the hippocampus, olfactory bulb and other regions of the rat forebrain by autoradiographic methods

1983 • 53 citations

Changes in hippocampal immunoreactive dynorphin and -neoendorphin content following intra-amygdalar kainic acid-induced seizures

1983 • 45 citations

Opiate modification of amygdaloid-kindled seizures in rats

1982 • 44 citations

Repeated electroconvulsive shock downregulates the opioid receptors in rat brain

1985 • 43 citations

Evidence for an agonist independent down regulation of hippocampal muscarinic receptors in kindling

1980 • 42 citations

Self-administration of dynorphin-[1–13] and D-ala2-dynorphin-[1–11] (kappa opioid agonists) in morphine (mu opioid agonist)-dependent rats

1983 • 35 citations

The effect of gamma-hydroxybutyrate and anticonvulsants on opioid peptide content in the rat brain

1983 • 34 citations

Opioid peptides, particularly dynorphin, after amygdaloid-kindled seizures

1983 • 30 citations

Mu opioid receptors participate in the excitatory effect of opiates in the hippocampal slice.

1984 • 27 citations

Correlation between the distribution of 3H-labelled enkephalin in rat brain and the anatomical regions involved in enkephalin-induced seizures

1983 • 25 citations

Brain content of Leu5- and Met5-enkephalin changes independently during the development of kindling in the rat

1981 • 22 citations

Changes in Simple and Complex Behaviors Following Kindled Seizures in Rats: Opioid and Nonopioid Mediation

1983 • 20 citations