Microtubule assembly protects the region 28–38 of the β‐ tubulin subunit

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Promotion of microtubule assembly in vitro by taxol

1979 • 3,521 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

A protein factor essential for microtubule assembly.

1975 • 2,863 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

Taxol binds to polymerized tubulin in vitro

1981 • 618 citations

Hydrophobic cluster analysis: An efficient new way to compare and analyse amino acid sequences

1987 • 616 citations

Solid-Phase Peptide Synthesis. III. An Improved Synthesis of Bradykinin^*

1964 • 555 citations

Epitopes on protein antigens: Misconceptions and realities

1990 • 532 citations

Arrangement of subunits in flagellar microtubules

1974 • 501 citations

Taxol binds to cellular microtubules.

1982 • 408 citations

Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes.

1986 • 403 citations

Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxin

1970 • 391 citations

Taxol assembles tubulin in the absence of exogenous guanosine 5'-triphosphate or microtubule-associated proteins

1981 • 369 citations

Interaction of drugs with microtubule proteins.

1974 • 349 citations

Complete amino acid sequence of beta-tubulin from porcine brain.

1981 • 303 citations

The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype.

1986 • 276 citations

The binding of vincristine, vinblastine and colchicine to tubulin

1972 • 273 citations

Complete amino acid sequence of alpha-tubulin from porcine brain.

1981 • 272 citations

Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction

1984 • 266 citations

Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly.

1984 • 251 citations

Aggregation of microtubule subunit protein. Effects of divalent cations, colchicine, and vinblastine

1970 • 237 citations

Tubulin domains probed by limited proteolysis and subunit-specific antibodies

1985 • 224 citations

A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. I. Biochemical characterization, effects on microtubule polymerization in vitro, and microtubule polymerization and organization in vivo.

1983 • 197 citations

Differential distribution of beta-tubulin isotypes in cerebellum.

1988 • 154 citations

Binding of maytansine to rat brain tubulin

1976 • 123 citations

Monoclonal antibodies that recognize discrete forms of tubulin.

1982 • 113 citations

Structural differences between brain beta 1- and beta 2-tubulins: implications for microtubule assembly and colchicine binding.

1985 • 110 citations

Tubulin domains responsible for assembly of dimers and protofilaments.

1985 • 97 citations

Proteolysis of tubulin and the substructure of the tubulin dimer.

1986 • 88 citations

The GTP-binding peptide of beta-tubulin. Localization by direct photoaffinity labeling and comparison with nucleotide-binding proteins.

1988 • 85 citations

Differences in the exposure of c- and n-terminal tubulin domains in cytoplasmic microtubules detected with domain-specific monoclonal antibodies

1989 • 77 citations

A combination of posttranslational modifications is responsible for the production of neuronal α‐tubulin heterogeneity

1991 • 68 citations

Tubulin sequence region beta 155-174 is involved in binding exchangeable guanosine triphosphate.

1987 • 61 citations

Analysis of β‐tubulin sequences reveals highly conserved, coordinated amino acid substitutions

1990 • 55 citations

Tubulin structure probed with antibodies to synthetic peptides. Mapping of three major types of limited proteolysis fragments

1988 • 53 citations

Tubulin assembly probed with antibodies to synthetic peptides

1990 • 49 citations

Criteria for distinguishing between the rapid equilibrium Ordered and Random Bi Bi kinetic mechanisms

1976 • 44 citations

Three-dimensional image of tubulin in zinc-induced sheets, reconstructed from electron micrographs

1979 • 35 citations

Posttranslational modifications of tubulin in cultured mouse brain neurons and astroglia

1989 • 35 citations

Antibodies to synthetic peptides from the tubulin regulatory domain interact with tubulin and microtubules.

1988 • 33 citations

Vincristine-induced self-association of calf brain tubulin

1985 • 30 citations

Location of the regions recognized by five commercial antibodies on the tubulin molecule

1986 • 30 citations

Interactions of Vinblastine and Maytansine with Tubulina

1986 • 28 citations

Location of the epitope for the α-tubulin monoclonal antibody TU-O1

1987 • 27 citations

Absence of 7‐acetyl taxol binding to unassembled brain tubulin

1988 • 27 citations

Inhibition of tubulin self-assembly in vitro by fluorodinitrobenzene

1981 • 22 citations

Immunological detection of microtubule poison-induced conformational changes in tubulin.

1983 • 21 citations

Monoclonal antibodies localize the exchangeable GTP‐binding site in β‐ and not α‐tubulins

1985 • 20 citations

Disruption of microtubules in living cells and cell models by high affinity antibodies to beta-tubulin.

1985 • 18 citations

Tubulin‐Colchicine Interactions and Polymerization of the Complexa

1986 • 17 citations

Involvement of tryptophan residues in colchicine binding and the assembly of tubulin

1982 • 13 citations

The removal of the carboxy-terminal region of tubulin favors its vinblastine-induced aggregation into spiral-like structures

1986 • 13 citations

Inhibition of microtubule assembly in vitro by anti-tubulin monoclonal antibodies

1990 • 5 citations

Posttranslational modifications of tubulin in cultured mouse brain neurons and astroglia

1989 • 5 citations