Effects of pyridine nucleotides on the gating of ATP-sensitive potassium channels in insulin-secreting cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

Electrophysiology of the pancreatic β-cell

1989 • 1,123 citations

Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells

1984 • 1,099 citations

Pancreatic islet glucose metabolism and regulation of insulin secretion

1986 • 506 citations

Mechanism of glucose-induced insulin secretion.

1980 • 425 citations

The stimulus-secretion coupling of glucose-induced insulin release

1979 • 420 citations

Glucose dependent K+-channels in pancreatic?-cells are regulated by intracellular ATP

1985 • 388 citations

Glucose‐induced electrical activity in pancreatic islet cells

1970 • 364 citations

Insulin release: The fuel hypothesis

1979 • 351 citations

Properties of adenosine‐triphosphate‐regulated potassium channels in guinea‐pig ventricular cells.

1985 • 344 citations

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

1984 • 324 citations

Glucoreceptor mechanisms and the control of insulin release and biosynthesis

1980 • 280 citations

A metabolite-regulated potassium channel in rat pancreatic B cells.

1986 • 277 citations

Electrophysiology of the pancreas.

1987 • 259 citations

The ATP‐sensitivity of K⁺ channels in rat pancreatic B‐cells is modulated by ADP

1986 • 242 citations

Regulation of immunoreactive-insulin release from a rat cell line (RINm5F)

1983 • 240 citations

Intracellular ADP activates K⁺ channels that are inhibited by ATP in an insulin‐secreting cell line

1986 • 227 citations

Dual effects of ATP on K+ currents of mouse pancreatic ?-cells

1987 • 158 citations

Electrical characteristics of pancreatic islet cells.

1975 • 145 citations

ATP-sensitive inward rectifier and voltage- and calcium-activated K+ channels in cultured pancreatic islet cells

1985 • 144 citations

ATP maintains ATP-inhibited K+ channels in an operational state

1986 • 139 citations

Quinine inhibits Ca²⁺‐independent K⁺ channels whereas tetraethylammonium inhibits Ca²⁺‐activated K⁺ channels in insulin‐secreting cells

1985 • 138 citations

Interaction of diazoxide, tolbutamide and ATP4− on nucleotide-dependent K+ channels in an insulin-secreting cell line

1987 • 132 citations

Glucose-induced changes in cytosolic ATP content in pancreatic islets

1987 • 120 citations

Glucose-induced decrease in Rb+ permeability in pancreatic β cells

1975 • 105 citations

Abnormal glucose metabolism accompanies failure of glucose to stimulate insulin release from a rat pancreatic cell line (RINm5F)

1983 • 103 citations

Similarities in the Stimulus-Secretion Coupling Mechanisms of Glucose- and 2-Keto Acid-Induced Insulin Release*

1980 • 99 citations

Signal Transduction in Insulin Secretion:.

1986 • 96 citations

Electrical characteristics of the beta-cells in pancreatic islets.

1976 • 89 citations

The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine.

1982 • 84 citations

Effect of carbohydrates upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets

1973 • 80 citations

Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion

1987 • 73 citations

The stimulus-secretion coupling of amino acid-induced insulin release. Influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets.

1982 • 70 citations

The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state

1984 • 68 citations

ATP-sensitive K+ channels in an insulin-secreting cell line are inhibited byd-glyceraldehyde and activated by membrane permeabilization

1986 • 65 citations

GTP and GDP activation of K+ channels that can be inhibited by ATP

1986 • 59 citations

Regulation by cell metabolism and adenine nucleotides of a K channel in insulin-secreting B cells (RIN m5F).

1987 • 52 citations

Metabolic concomitants in pure, pancreatic beta cells during glucose-stimulated insulin secretion.

1986 • 50 citations

Effects of glucose on the cytosolic ration of reduced/oxidized nicotinamide-adenine dinucleotide phosphate in rat islets of Langerhans

1979 • 45 citations

The stimulus–secretion coupling 4-methyl-2-oxopentanoate-induced insulin release

1979 • 33 citations

Signal Transduction in Insulin Secretion:.

1986 • 21 citations

HPLC analysis of nucleotide profiles in glucose-stimulated perifused rat islets

1987 • 17 citations