Structure of the NMDA Receptor Channel M2 Segment Inferred from the Accessibility of Substituted Cysteines

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Single-Channel Recording

1995 • 2,565 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

1993 • 978 citations

Excitatory amino acid receptors and synaptic plasticity

1990 • 872 citations

Contrasting properties of two forms of long-term potentiation in the hippocampus

1995 • 839 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants

1992 • 668 citations

Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes.

1995 • 440 citations

Control by Asparagine Residues of Calcium Permeability and Magnesium Blockade in the NMDA Receptor

1992 • 437 citations

Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices.

1992 • 435 citations

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1

1994 • 419 citations

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the α subunit

1994 • 418 citations

Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop

1995 • 293 citations

Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

1994 • 255 citations

Multiple Structural Elements Determine Subunit Specificity of Mg²⁺Block in NMDA Receptor Channels

1996 • 228 citations

Transmembrane topology of two kainate receptor subunits revealed by N-glycosylation.

1994 • 196 citations

Voltage-dependent block by intracellular Mg2+ of N-methyl-D-aspartate-activated channels

1990 • 186 citations

Structural conservation of ion conduction pathways in K channels and glutamate receptors.

1995 • 158 citations

Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors

1995 • 143 citations

The role of Ca2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation

1993 • 140 citations

Ionic channels of excitable membranes. Second edition

1992 • 129 citations

Dimensions of the narrow portion of a recombinant NMDA receptor channel

1995 • 122 citations

Exposure of Residues in the Cyclic Nucleotide–Gated Channel Pore: P Region Structure and Function in Gating

1996 • 118 citations

Differential contribution of the NR1‐ and NR2A‐subunits to the selectivity filter of recombinant NMDA receptor channels.

1996 • 113 citations

A monovalent cationic conductance that is blocked by extracellular divalent cations in Xenopus oocytes.

1995 • 71 citations

The Giant Membrane Patch

1995 • 68 citations