Botulinum E Toxin Light Chain Does Not Cleave SNAP-23 and Only Partially Impairs Insulin Stimulation of GLUT4 Translocation in 3T3-L1 Cells

Mechanisms of intracellular protein transport

1994 • 2,280 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane.

1980 • 1,066 citations

Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site.

1980 • 1,042 citations

Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

1994 • 798 citations

The syntaxin family of vesicular transport receptors

1993 • 656 citations

Identification of a Novel Syntaxin- and Synaptobrevin/VAMP-binding Protein, SNAP-23, Expressed in Non-neuronal Tissues

1996 • 356 citations

Clostridial neurotoxins: new tools for dissecting exocytosis

1994 • 323 citations

Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

1997 • 309 citations

A conserved domain is present in different families of vesicular fusion proteins: A new superfamily

1997 • 308 citations

Members of the VAMP family of synaptic vesicle proteins are components of glucose transporter-containing vesicles from rat adipocytes.

1992 • 275 citations

SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

1995 • 243 citations

Syntaxin 4, VAMP2, and/or VAMP3/Cellubrevin Are Functional Target Membrane and Vesicle SNAP Receptors for Insulin-Stimulated GLUT4 Translocation in Adipocytes

1997 • 236 citations

Membrane trafficking in the presynaptic nerve terminal

1995 • 217 citations

Characterization of Munc-18c and Syntaxin-4 in 3T3-L1 Adipocytes

1997 • 213 citations

The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells.

1996 • 211 citations

Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins

1996 • 175 citations

Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment.

1995 • 154 citations

SNAP-25 Is Required for a Late Postdocking Step in Ca2+-dependent Exocytosis

1996 • 148 citations

The Metabolic Regulation and Vesicular Transport of GLUT4, the Major Insulin-Responsive Glucose Transporter*

1995 • 142 citations

Syntaxin 4 in 3T3-L1 adipocytes: regulation by insulin and participation in insulin-dependent glucose transport.

1996 • 135 citations

The glucose transporter GluT4 and secretory carrier membrane proteins (SCAMPs) colocalize in rat adipocytes and partially segregate during insulin stimulation.

1993 • 121 citations

Structural Determinants of the Specificity for Synaptic Vesicle-associated Membrane Protein/Synaptobrevin of Tetanus and Botulinum Type B and G Neurotoxins

1996 • 116 citations

Cellubrevin Is a Resident Protein of Insulin-sensitive GLUT4 Glucose Transporter Vesicles in 3T3-L1 Adipocytes

1995 • 115 citations

Syndet is a novel SNAP-25 related protein expressed in many tissues

1997 • 110 citations

Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes.

1995 • 79 citations

Immunological analysis of GLUT4-enriched vesicles. Identification of novel proteins regulated by insulin and diabetes

1993 • 72 citations

Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line

1994 • 68 citations

Tissue Distribution of SNAP-23 and Its Subcellular Localization in 3T3-L1 Cells

1997 • 68 citations

Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein

1996 • 67 citations

Cleavage of Vesicle-Associated Membrane Protein (VAMP)-2 and Cellubrevin on GLUT4-Containing Vesicles Inhibits the Translocation of GLUT4 in 3T3-L1 Adipocytes

1996 • 67 citations

Expression of the synaptic vesicle proteins VAMPs/synaptobrevins 1 and 2 in non-neural tissues.

1994 • 61 citations

Botulinum Neurotoxin B Inhibits Insulin-Stimulated Glucose Uptake into 3T3-L1 Adipocytes and Cleaves Cellubrevin Unlike Type A Toxin Which Failed To Proteolyze the SNAP-23 Present

1997 • 54 citations

Identification of Two Isoforms of the Vesicle-Membrane Fusion Protein SNAP-23 in Human Neutrophils and HL-60 Cells

1997 • 52 citations

Functional studies in 3T3L1 cells support a role for SNARE proteins in insulin stimulation of GLUT4 translocation

1997 • 49 citations

Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2

1996 • 46 citations

Cyclic AMP acutely stimulates translocation of the major insulin-regulatable glucose transporter GLUT4.

1992 • 44 citations

Novel isoform of syntaxin 1 is expressed in mammalian cells

1997 • 31 citations

Expression of Syntaxin 4 in Rat Skeletal Muscle and Rat Skeletal Muscle Cells in Culture

1995 • 30 citations

Proteolytic cleavage of cellubrevin and vesicle-associated membrane protein (VAMP) by tetanus toxin does not impair insulin-stimulated glucose transport or GLUT4 translocation in rat adipocytes

1997 • 21 citations