Possible Involvement of CTL Granule Proteases in Target Cell DNA Breakdown

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1987 • 393 citations

Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors.

1984 • 337 citations

Sulfonyl Fluorides as Inhibitors of Esterases. II. Formation and Reactions of Phenylmethanesulfonyl α-Chymotrypsin^*

1964 • 294 citations

Serine esterase in cytolytic T lymphocytes

1986 • 240 citations

Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes.

1983 • 229 citations

Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage

1983 • 225 citations

Cytotoxic T lymphocyte mediated lysis without release of serine esterase

1987 • 196 citations

Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes

1987 • 174 citations

The translational mobility of substances within the cytoplasmic matrix.

1984 • 154 citations

Specific release of proteoglycans from human natural killer cells during target lysis

1985 • 146 citations

Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.

1987 • 128 citations

Differences in target cell DNA fragmentation induced by mouse cytotoxic T lymphocytes and natural killer cells.

1986 • 102 citations

Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes

1986 • 83 citations

T-lymphocyte-mediated cytolysis as an excitatory process of the target

1985 • 71 citations

Biochemical and functional properties of serine esterases in acidic cytoplasmic granules of cytotoxic T lymphocytes.

1987 • 70 citations

Permeability changes induced in erthrocyte ghost targets by antibody-dependent cytotoxic effector cells: evidence for membrane pores.

1980 • 62 citations

Extracellular release of lymphocyte cytolytic pore-forming protein (perforin) after ionophore stimulation.

1986 • 61 citations

Evidence for control of mast cell granule protease in situ by low pH*1

1983 • 42 citations

Functional histone antibody fragments traverse the nuclear envelope.

1984 • 42 citations

The Role of Cytoplasmic Granules in Lymphocyte Cytotoxicity

2015 • 39 citations

Are lytic granules and perforin 1 involved in lysis induced by in vivo-primed peritoneal exudate cytolytic T lymphocytes?

1987 • 37 citations

Role of granule proteins in lymphocyte‐mediated killing

1986 • 37 citations