Complex regulation of tumor necrosis factor mRNA turnover in lipopolysaccharide-activated macrophages

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

1989 • 1,269 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Tumors secreting human TNF/cachectin induce cachexia in mice

1987 • 634 citations

Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease.

1987 • 609 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.

1989 • 578 citations

Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.

1990 • 509 citations

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.

1990 • 495 citations

Increased Plasma Tumor Necrosis Factor in Severe Alcoholic Hepatitis

1990 • 470 citations

Translational Blockade Imposed by Cytokine-Derived UA-Rich Sequences

1989 • 347 citations

Studies of endotoxin-induced decrease in lipoprotein lipase activity.

1981 • 333 citations

Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes.

1988 • 227 citations

Cytokines in synovial fluid: II. The presence of tumour necrosis factor and interferon.

1988 • 191 citations

The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids.

1991 • 170 citations

Interactive effects of the tumor necrosis factor promoter and 3'-untranslated regions.

1991 • 153 citations

2‐Aminopurine selectively blocks the transcriptional activation of cellular genes by virus, double‐stranded RNA and interferons in human cells

1989 • 64 citations

Identification of a translation inhibitory element (TIE) in the 3′ untranslated region of the human interferon-β mRNA

1988 • 59 citations

Immunohistochemical studies of intrahepatic tumour necrosis factor alpha in chronic liver disease.

1990 • 43 citations